Neurocritical Care

, Volume 9, Issue 2, pp 237–241

Eligibility for the Surgical Trial in Intracerebral Hemorrhage II Study in a Population-based Cohort

  • Opeolu Adeoye
  • Daniel Woo
  • Mary Haverbusch
  • Haiyang Tao
  • Padmini Sekar
  • Charles J. Moomaw
  • Lori Shutter
  • Dawn Kleindorfer
  • Brett Kissela
  • Joseph Broderick
  • Matthew L. Flaherty
Original Article

DOI: 10.1007/s12028-007-9045-8

Cite this article as:
Adeoye, O., Woo, D., Haverbusch, M. et al. Neurocrit Care (2008) 9: 237. doi:10.1007/s12028-007-9045-8
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Abstract

Introduction

No proven treatments exist for intracerebral hemorrhage (ICH). Carefully selected patients may benefit from surgery, and an international multicenter trial is ongoing. We sought to determine how many patients in a population-based ICH cohort would have been eligible for surgery using the Surgical Trial in Intracerebral Hemorrhage II (STICH II) criteria.

Methods

We identified all patients aged ≥18 years residing in the five-county Greater Cincinnati region who were hospitalized with first-ever nontraumatic ICH in 2005. STICH II trial criteria were used to determine eligibility for treatment and reasons for exclusion.

Results

During 2005, 286 ICH patients were identified (103 lobar, 126 deep cerebral, 23 brainstem, 28 cerebellar, and 6 IVH). Non-lobar hemorrhages are not eligible for STICH II. Among patients with lobar hemorrhage, 22 had no exclusions. The most common (not mutually exclusive) reasons for exclusion were volume <10 cc or >100 cc (n = 46) and presence of IVH (n = 27). No significant age, gender or racial differences existed between eligible and ineligible patients with lobar ICH. Only one (4.5%) of the 22 STICH II eligible patients in our population had surgery, compared with eight of 81 (9.9%) ineligible lobar ICH patients (P = 0.43). Mortality at 180 days in STICH II eligible patients was 36% vs. 49% for ineligible lobar ICH patients (P = 0.19).

Conclusions

In this population-based ICH cohort, 7.7% (22 of 286) of ICH patients would have qualified for STICH II enrollment. Other treatment options need to be explored for most ICH patients.

Keywords

Acute stroke Intracerebral hemorrhage Neurosurgery Surgery 

Copyright information

© Humana Press Inc. 2008

Authors and Affiliations

  • Opeolu Adeoye
    • 1
    • 2
  • Daniel Woo
    • 3
  • Mary Haverbusch
    • 3
  • Haiyang Tao
    • 4
  • Padmini Sekar
    • 5
  • Charles J. Moomaw
    • 3
  • Lori Shutter
    • 3
    • 6
  • Dawn Kleindorfer
    • 3
  • Brett Kissela
    • 3
  • Joseph Broderick
    • 3
  • Matthew L. Flaherty
    • 3
  1. 1.Department of Emergency MedicineUniversity of CincinnatiCincinnatiUSA
  2. 2.Department of Emergency MedicineUniversity of Cincinnati Medical CenterCincinnatiUSA
  3. 3.Department of NeurologyUniversity of CincinnatiCincinnatiUSA
  4. 4.University of Cincinnati College of MedicineCincinnatiUSA
  5. 5.Department of Environmental HealthUniversity of CincinnatiCincinnatiUSA
  6. 6.Department of NeurosurgeryUniversity of CincinnatiCincinnatiUSA

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