An interdisciplinary review of the thanatomicrobiome in human decomposition
Death does not occur instantaneously and organs do not decompose at the same rate or in the same way. Nulligravid human uteri and prostate glands are the last internal organs to deteriorate during decomposition; however, the reason for this very important observation is still enigmatic. Recent studies have elucidated that the composition and abundance of microbes in the human thanatomicrobiome (microbiome of death) varies by organ and changes as a function of time and temperature. The ileocecal area has the largest absolute postmortem burden that spreads to the liver and spleen and continues to the heart and brain depending on the cause of death. To truly understand the mechanisms of microbial assembly during decomposition, a thorough examination of different strategies utilized by the trillions of microbes that colonize decaying tissues is needed from a multi-organ and multidisciplinary approach. In this review, we highlight interdisciplinary research and provide an overview of human decomposition investigations of thanatomicrobiomic changes in internal organs.
KeywordsHuman decomposition Internal organs Thanatomicrobiome Postmortem microbiome
This review paper was supported by National Science Foundation HRD 1401075 and National Institute of Justice 2017-MU-MU-0042 grants.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflicts of interest.
Human and animal studies
The authors declare that no research involving human participants and/or animals was conducted in this review.
No identifying information about participants was used in this review.
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