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Endocrine Pathology

, Volume 28, Issue 2, pp 152–158 | Cite as

Adrenal Teratoma: a Case Series and Review of the Literature

  • Eric J. Kuo
  • Anthony E. Sisk
  • Zhiming Yang
  • Jiaoti Huang
  • Michael W. Yeh
  • Masha J. Livhits
Article

Abstract

Adrenal teratomas are rare neoplasms and there is limited data on their surgical outcomes and long-term prognosis. We aimed to review our institutional experience and compare this to the existing literature on adrenal teratomas in adults and children. An institutional pathology database was searched for cases of adrenal teratoma (June 1956–July 2016). Clinical and imaging data were abstracted from the medical records and pathology slides were obtained for review. In addition, a PubMed search for “adrenal teratoma” from June 1952 to July 2016 was performed to identify reports of primary adrenal teratoma in patients of all ages. Of 7706 patients who underwent adrenalectomy during the study period at our institution, three patients were identified with adrenal teratoma. Patients were 24, 26, and 29 years of age, respectively. Two patients presented with abdominal pain and two of the three underwent a laparoscopic adrenalectomy. A pathologic examination revealed mature cystic teratomas that frequently displayed well-differentiated respiratory, digestive, and squamous epithelia. Eighteen case reports in the literature were identified in patients 17–61 years of age. Patients presented most frequently with abdominal or flank pain (63.6%). Median tumor diameter was 9.0 cm and tumors were frequently left-sided (81.8%), cystic (63.6%), and calcified (72.7%) on either radiologic or pathologic examination. Primary adrenal teratomas are rare neoplasms that typically present as large, left-sided nodules with cystic and calcified components seen radiographically. Although the data are limited, they are generally amenable to laparoscopic resection and have a very favorable prognosis.

Keywords

Teratoma Adrenal Retroperitoneal Adrenalectomy 

Notes

Acknowledgments

This publication was supported in part by the H H Lee Research Program.

Compliance with Ethical Standards

Statement of Human Rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  • Eric J. Kuo
    • 1
  • Anthony E. Sisk
    • 2
  • Zhiming Yang
    • 2
  • Jiaoti Huang
    • 2
  • Michael W. Yeh
    • 1
  • Masha J. Livhits
    • 1
  1. 1.Section of Endocrine SurgeryUCLA David Geffen School of MedicineLos AngelesUSA
  2. 2.Department of Pathology and Laboratory MedicineUCLA David Geffen School of MedicineLos AngelesUSA

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