Endocrine Pathology

, Volume 26, Issue 2, pp 152–156 | Cite as

Epithelioid Angiosarcoma of the Thyroid: Report of a Case from an Italian Non-Alpine Area and Review of the Literature

  • Matteo RotelliniEmail author
  • Vania Vezzosi
  • Simonetta Bianchi


Epithelioid angiosarcoma of the thyroid is a rare mesenchymal neoplasm, mainly described in the Alpine area. This lesion was initially considered an anaplastic carcinoma, but immunohistochemical and ultrastructural features have proven the endothelial differentiation of tumor cells. In fact, the peculiarity of this tumor concerns the expression of low-molecular weight cytokeratins by neoplastic cells of endothelial origin. We describe a case of epithelioid angiosarcoma of the thyroid occurred in a 73-year-old woman from an Italian non-Alpine area, and a review of non-Alpine primary thyroid epitheliod angiosarcoma is presented.


Thyroid Epitheliod angiosarcoma Immunohistochemistry Cytokeratin 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Matteo Rotellini
    • 1
    Email author
  • Vania Vezzosi
    • 1
  • Simonetta Bianchi
    • 1
  1. 1.Pathological Anatomy Unit, Department of Surgery and Translational MedicineUniversity of FlorenceFlorenceItaly

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