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Endocrine Pathology

, Volume 24, Issue 4, pp 239–245 | Cite as

Follicular Thyroid Carcinoma with Signet Ring Cell Morphology: Fine-Needle Aspiration Cytology, Histopathology, and Immunohistochemistry

  • Alfredo E. Romero-Rojas
  • Julio A. Diaz-PerezEmail author
  • Melina Mastrodimos
  • Sandra I. Chinchilla
Article

Abstract

Thyroid follicular neoplasms with signet ring cell morphology represent a challenging cytological and histopathologic diagnosis. The low frequency of these neoplasms and their broad differential diagnosis contribute to this difficult scenario. Here, we present an exceptionally rare case of thyroid follicular carcinoma with signet ring cell morphology in a 62-year-old female. We analyze the characteristics in fine-needle aspiration cytology, histopathology, and immunohistochemistry and compare our results in a discussion with previous literature reports.

Keywords

Follicular thyroid carcinoma Signet ring cell Cytology Histopathology 

Notes

Conflict of interest

There are no conflicts of interest to disclose.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Alfredo E. Romero-Rojas
    • 1
  • Julio A. Diaz-Perez
    • 1
    • 2
    • 3
    Email author
  • Melina Mastrodimos
    • 2
  • Sandra I. Chinchilla
    • 1
  1. 1.National Institute of CancerBogotaColombia
  2. 2.University of CaliforniaSan DiegoUSA
  3. 3.University of SantanderBucaramangaColombia

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