Macrofollicular Variant of Follicular Thyroid Carcinoma: A Case Report
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A 37-year-old female known for systemic lupus erythematosus underwent a right thyroid lobectomy for a growing nodule in the right lobe. A fine-needle aspiration biopsy (FNAB) performed 4 years before surgery reported a microfollicular proliferation. A second FNAB performed a few months before surgery revealed a benign lesion. The surgical specimen was fixed in 4 % buffered formaldehyde. The entire nodule was sampled, with particular attention to the capsule, and embedded in paraffin and corresponding sections were stained with hematoxylin and eosin for histological examination. Immunohistochemistry using HBME1 and galectin-3 was performed.
What is Your Diagnosis?
The pathological diagnosis of the patient was follicular thyroid carcinoma, macrofollicular variant, which is minimally invasive, stage pT2 pNX.
KeywordsSystemic Lupus Erythematosus Papillary Thyroid Carcinoma Thyroid Nodule Follicular Thyroid Carcinoma Follicular Adenoma
- 1.Rosai JCM, DeLellis R: Atlas of Tumor Pathology: Tumors of the Thyroid Gland, series 3. Washington, Armed Forces Institute of Pathology, 1992.Google Scholar