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Endocrine Pathology

, Volume 24, Issue 3, pp 167–168 | Cite as

Macrofollicular Variant of Follicular Thyroid Carcinoma: A Case Report

  • Claudio De Vito
  • Massimo Bongiovanni
  • Frederic Triponez
  • Marc PusztaszeriEmail author
Article

Case Report

A 37-year-old female known for systemic lupus erythematosus underwent a right thyroid lobectomy for a growing nodule in the right lobe. A fine-needle aspiration biopsy (FNAB) performed 4 years before surgery reported a microfollicular proliferation. A second FNAB performed a few months before surgery revealed a benign lesion. The surgical specimen was fixed in 4 % buffered formaldehyde. The entire nodule was sampled, with particular attention to the capsule, and embedded in paraffin and corresponding sections were stained with hematoxylin and eosin for histological examination. Immunohistochemistry using HBME1 and galectin-3 was performed.

What is Your Diagnosis?

The pathological diagnosis of the patient was follicular thyroid carcinoma, macrofollicular variant, which is minimally invasive, stage pT2 pNX.

On gross section, the nodule measured 4 × 4 × 3.5 cm. It was encapsulated with a shiny colloidal appearance without calcification (Fig.  1a). On histology, the nodule was...

Keywords

Systemic Lupus Erythematosus Papillary Thyroid Carcinoma Thyroid Nodule Follicular Thyroid Carcinoma Follicular Adenoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Claudio De Vito
    • 1
  • Massimo Bongiovanni
    • 2
  • Frederic Triponez
    • 3
  • Marc Pusztaszeri
    • 1
    Email author
  1. 1.Department of Clinical PathologyGeneva University HospitalGeneva 14Switzerland
  2. 2.Institute of PathologyLocarnoSwitzerland
  3. 3.Department of Thoracic and Endocrine SurgeryGeneva University HospitalGenevaSwitzerland

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