, Volume 5, Issue 3, pp 161–175

Sharing and Reusing Gene Expression Profiling Data in Neuroscience


DOI: 10.1007/s12021-007-0012-5

Cite this article as:
Wan, X. & Pavlidis, P. Neuroinform (2007) 5: 161. doi:10.1007/s12021-007-0012-5


As public availability of gene expression profiling data increases, it is natural to ask how these data can be used by neuroscientists. Here we review the public availability of high-throughput expression data in neuroscience and how it has been reused, and tools that have been developed to facilitate reuse. There is increasing interest in making expression data reuse a routine part of the neuroscience tool-kit, but there are a number of challenges. Data must become more readily available in public databases; efforts to encourage investigators to make data available are important, as is education on the benefits of public data release. Once released, data must be better-annotated. Techniques and tools for data reuse are also in need of improvement. Integration of expression profiling data with neuroscience-specific resources such as anatomical atlases will further increase the value of expression data.


Microarray Gene expression analysis Meta-analysis 

Copyright information

© Humana Press Inc. 2007

Authors and Affiliations

  1. 1.Department of Psychiatry, UBC Bioinformatics Centre (UBiC)University of British ColumbiaVancouverCanada

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