Dual-release hydrocortisone is a new hydrocortisone formulation developed to improve the pharmacokinetic and the pharmacodynamic profiles and patient compliance. The aim of this review is to summarize the main knowledge on dual-release hydrocortisone, with particular attention to pharmacokinetics, metabolic and health-related quality-of-life aspects, bone health and drug safety.
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Mongioì, L.M., Condorelli, R.A., Barbagallo, F. et al. Dual-release hydrocortisone for treatment of adrenal insufficiency: a systematic review. Endocrine (2020) doi:10.1007/s12020-020-02187-7
- Adrenal insufficiency
- Dual-release hydrocortisone