, Volume 66, Issue 3, pp 477–484 | Cite as

Multidisciplinary team efforts improve the surgical outcomes of sellar region lesions during pregnancy

  • Hui Ping Zhong
  • Hao Tang
  • Yong Zhang
  • Yan Luo
  • Hong Yao
  • Yu Cheng
  • Wei Ting Gu
  • Yong Xu Wei
  • Zhe Bao WuEmail author
Endocrine Surgery



Treatment of space-occupying lesions (SOLs) in the sellar region is a clinical challenge, especially in pregnant women because many treatment decisions are restrained due to pregnancy. We attempt to discuss the surgical indications and timing for pregnant patients and highlight the importance of multidisciplinary team (MDT) treatment.


From August 2017 to February 2018, four pregnant women were admitted to our hospital with severe visual impairment due to sellar region SOLs, including two cases of tuberculum sellae meningioma, one case of giant pituitary adenoma and one case of a pituitary abscess. All four patients were safely treated by surgery during the second and third trimesters of pregnancy through concerted efforts of the MDT, including a neurosurgeon as the team leader in combination with experts in obstetrics, ophthalmology and endocrinology.


The SOLs were removed completely from all four patients, resulting in significantly improved vision without operation-related complications. Pregnancy continued postoperatively to full-term delivery in three of the four patients. The other patient with a pituitary abscess selected to terminate the pregnancy at a gestational age of 20 weeks because of her own concerns. The four babies (including a pair of twins) were born healthy and had developed normally at the 6-week postpartum follow-up.


With the MDT guiding the decision-making process, surgical resection of sellar region SOLs in pregnant women with severe visual impairment is practical to improve the prognosis without affecting the outcomes of pregnancy for either the mother or the infant.


Multidisciplinary team (MDT) Pregnancy Sellar region lesion Visual impairment 



This study was funded by Shanghai Science and Technology Commission and Program of Shanghai Academic Research Leader (ZBW) (grant number: 18XD1403400).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Hui Ping Zhong
    • 1
  • Hao Tang
    • 2
  • Yong Zhang
    • 2
  • Yan Luo
    • 3
  • Hong Yao
    • 2
  • Yu Cheng
    • 4
  • Wei Ting Gu
    • 2
  • Yong Xu Wei
    • 2
  • Zhe Bao Wu
    • 2
    Email author
  1. 1.Department of Obstetrics, Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina
  2. 2.Department of Neurosurgery, Center of Pituitary TumorRuijin Hospital, Shanghai Jiao Tong University School of MedicineShanghaiChina
  3. 3.Department of Anesthesiology, Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina
  4. 4.Department of Ophthalmology, Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

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