Advertisement

Endocrine

, Volume 63, Issue 1, pp 188–189 | Cite as

18F-FDG PET reveals an adrenocortical carcinoma in a bilateral adrenal multinodular disease

  • Rossella LibéEmail author
  • Jean-François Jazeron
  • Estelle Louiset
  • Lionel Groussin
Endocrine Imaging
  • 56 Downloads
A 48-year-old man underwent an abdominal computed tomography (CT) scan for asthenia. The CT scan revealed bilateral adrenal masses. The left mass measured 47 × 27 mm with a spontaneous density (SD) of -6 Hounsfield Unit (HU), in favor of a benign adrenocortical lesion (adenoma if < 10 HU). The right adrenal presented one anterior nodule of 28 × 23 mm with a SD of −25 UH, in favor of a benign lesion and a second posterior nodule of 21 × 25 mm, with a high SD of 27 UH and an absolute washout of 55% (> 60% in case of a benign lesion), consistent with an indeterminate lesion (Fig. 1a). The patient was lost of follow-up. After 1 year, the patient was referred to our hospital for hypertension, hypokalaemia and android obesity. Hormonal investigations showed an ACTH-independent hypercortisolism (Urinary free cortisol: 373 nmol/24 h (normal values:69-248), ACTH < 2 pmol/l (normal values 2 to 13)). The CT scan showed an increase in the posterior right adrenal mass (85 × 66 mm) with multiple...

Notes

Acknowledgements

We thank the "Association Surrénales" for their technical assistance.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent was obtain from the patient to publish this report

References

  1. 1.
    M. Fassnacht, W. Arlt, I. Bancos et al. Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. Eur. J. Endocrinol. 175(2), G1–G34 (2016)CrossRefGoogle Scholar
  2. 2.
    L. Groussin, G. Bonardel, S. Silvéra et al. 18F-Fluorodeoxyglucose positron emission tomography for the diagnosis of adrenocortical tumors: a prospective study in 77 operated patients. J. Clin. Endocrinol. Metab. 945, 1713–1722 (2009)CrossRefGoogle Scholar
  3. 3.
    W. Fenske, H.U. Völker, P. Adam et al. Glucose transporter GLUT1 expression is an stage-independent predictor of clinical outcome in adrenocortical carcinoma. Endocr. Relat. Cancer 16, 919–928 (2009)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.COMETE Cancer Network for Adrenal Cancers, Department of EndocrinologyCochin HospitalParisFrance
  2. 2.Pathology UnitGroupe Hospitalier La RochelleLa RochelleFrance
  3. 3.Normandie UnivUNIROUEN, INSERM, DC2NRouenFrance

Personalised recommendations