, Volume 54, Issue 2, pp 560–561 | Cite as

Allocation of parathyroid adenoma and suspicious thyroid nodule by real-time 99mTc-MIBI SPECT/US fusion imaging

  • Falk Gühne
  • Henning Mothes
  • Martin FreesmeyerEmail author
Endocrine Imaging
A 58-year-old man presented with hypercalcemia caused by primary hyperparathyroidism (PTH: 290 ng/l). Imaging was performed for allocation of parathyroid adenoma. Ultrasonography (US) showed multinodular goiter with a large (4.5-cm diameter), hypoechoic, inhomogeneous, unsharp nodule caudally in the right lobe, representing potential criteria of malignancy. Caudodorsally, a small (1.5-cm diameter) hypoechoic lesion was detected with no further malignant signs whereby the differentiation toward the thyroid was sonomorphologically vague, leaving a marginal thyroid nodule or an enlarged parathyroid gland as potential differential diagnoses. 99mTc-pertechnetate scintigraphy proved both nodules to be hypofunctional (Fig.  1a). 99mTc-methoxyisobutylisonitrile (MIBI) scintigraphy (Fig.  1b) and single-photon emission computed tomography (SPECT; not shown) demonstrated a great area of reduced uptake in the right caudal part but a slight spot caudodorsally, which showed no correlation on 99mTc-pe...


Thyroid Cancer Goiter Thyroid Nodule Primary Hyperparathyroidism Parathyroid Adenoma 
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Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

Supplementary material 1 (WMV 5114 kb). Supplement 1: Magnetic sensor-navigated 99mTc-MIBI SPECT/US of right thyroid lobe, sagittal sweep from lateral to medial. The hypoechoic, MIBI-positive parathyroid adenoma caudodorsally is marked with a yellow arrow


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Falk Gühne
    • 1
  • Henning Mothes
    • 2
  • Martin Freesmeyer
    • 1
    Email author
  1. 1.Clinic of Nuclear MedicineJena University HospitalJenaGermany
  2. 2.Clinic of General, Visceral and Vascular SurgeryJena University HospitalJenaGermany

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