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Endocrine

, Volume 54, Issue 2, pp 560–561 | Cite as

Allocation of parathyroid adenoma and suspicious thyroid nodule by real-time 99mTc-MIBI SPECT/US fusion imaging

  • Falk Gühne
  • Henning Mothes
  • Martin FreesmeyerEmail author
Endocrine Imaging
A 58-year-old man presented with hypercalcemia caused by primary hyperparathyroidism (PTH: 290 ng/l). Imaging was performed for allocation of parathyroid adenoma. Ultrasonography (US) showed multinodular goiter with a large (4.5-cm diameter), hypoechoic, inhomogeneous, unsharp nodule caudally in the right lobe, representing potential criteria of malignancy. Caudodorsally, a small (1.5-cm diameter) hypoechoic lesion was detected with no further malignant signs whereby the differentiation toward the thyroid was sonomorphologically vague, leaving a marginal thyroid nodule or an enlarged parathyroid gland as potential differential diagnoses. 99mTc-pertechnetate scintigraphy proved both nodules to be hypofunctional (Fig.  1a). 99mTc-methoxyisobutylisonitrile (MIBI) scintigraphy (Fig.  1b) and single-photon emission computed tomography (SPECT; not shown) demonstrated a great area of reduced uptake in the right caudal part but a slight spot caudodorsally, which showed no correlation on 99mTc-pe...

Keywords

Thyroid Cancer Goiter Thyroid Nodule Primary Hyperparathyroidism Parathyroid Adenoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

Supplementary material 1 (WMV 5114 kb). Supplement 1: Magnetic sensor-navigated 99mTc-MIBI SPECT/US of right thyroid lobe, sagittal sweep from lateral to medial. The hypoechoic, MIBI-positive parathyroid adenoma caudodorsally is marked with a yellow arrow

References

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Falk Gühne
    • 1
  • Henning Mothes
    • 2
  • Martin Freesmeyer
    • 1
    Email author
  1. 1.Clinic of Nuclear MedicineJena University HospitalJenaGermany
  2. 2.Clinic of General, Visceral and Vascular SurgeryJena University HospitalJenaGermany

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