, Volume 42, Issue 1, pp 218–219 | Cite as

Henry VIII’s obesity following traumatic brain injury

  • Hutan Ashrafian
Letter to the Editor

To the Editor,

Henry VIII (1491–1547) is considered as one of the most prominent kings of England. Famous for his marriage to six wives and the renunciation of Roman Catholicism to establish the Anglican Church of England, Henry also bestowed patronage to several foundation medical institutes within the United Kingdom, which survive to this day. His modern image is frequently marred by a reputation for cruelty, pomposity and self-indulgence that were most notably manifest in his later years.

Although Henry VIII was celebrated for his health in youth, demonstrating an enthusiasm for equestrianism, hunting and combative sports, his physical condition declined such that he became morbidly obese, suffered from depression and was noted to have bilateral leg ulcers (“sorre legge”) that were possibly due to severe venous hypertension as a result of deep vein thromboses [1].

His health status is identified in several reports that offer evidence of the progressive change in his body habitus...


Traumatic Brain Injury Malaria Growth Hormone Deficiency Smallpox Venous Hypertension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    C.R. Chalmers, E.J. Chaloner, 500 years later: Henry VIII, leg ulcers and the course of history. J. R. Soc. Med. 102, 514–517 (2009)PubMedCrossRefGoogle Scholar
  2. 2.
    M. Keynes, The personality and health of King Henry VIII (1491–1547). J. Med. Biogr. 13, 174–183 (2005)PubMedGoogle Scholar
  3. 3.
    H.J. Schneider, I. Kreitschmann-Andermahr, E. Ghigo, G.K. Stalla, A. Agha, Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic review. JAMA 298, 1429–1438 (2007)PubMedCrossRefGoogle Scholar
  4. 4.
    V. Popovic, GH deficiency as the most common pituitary defect after TBI: clinical implications. Pituitary 8, 239–243 (2005)PubMedCrossRefGoogle Scholar
  5. 5.
    F.F. Casanueva, A.I. Castro, D. Micic, F. Kelestimur, C. Dieguez, New guidelines for the diagnosis of growth hormone deficiency in adults. Horm. Res. 71(1), 112–115 (2009)PubMedCrossRefGoogle Scholar
  6. 6.
    E. Ghigo, G. Aimaretti, G. Corneli, Diagnosis of adult GH deficiency. Growth Horm. IGF Res. 18, 1–16 (2008)PubMedCrossRefGoogle Scholar
  7. 7.
    R. Cimaz, R. Rusconi, E. Fossali, P. Careddu, Unexpected healing of cutaneous ulcers in a short child. Lancet 358, 211–212 (2001)PubMedCrossRefGoogle Scholar
  8. 8.
    V. Monafo, G.L. Marseglia, M. Maghnie, K.M. Dyne, G. Cetta, Transient beneficial effect of GH replacement therapy and topical GH application on skin ulcers in a boy with prolidase deficiency. Pediatr. Dermatol. 17, 227–230 (2000)PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Surgery and CancerImperial College LondonLondonUK

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