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Endocrine

, Volume 41, Issue 1, pp 19–30 | Cite as

Extrapituitary production of anterior pituitary hormones: an overview

  • S. HarveyEmail author
  • C. Arámburo
  • E. J. Sanders
Review

Abstract

Protein hormones from the anterior pituitary gland have well-established endocrine roles in their peripheral target glands. It is, however, now known that these proteins are also produced within many of their target tissues, in which they act as local autocrine or paracrine factors, with physiological and/or pathophysiological significance. This emerging concept is the focus of this brief review.

Keywords

Growth hormone Prolactin Adrenocorticotropin Thyrotropin Luteinizing hormone Follicle-stimulating hormone 

Notes

Acknowledgment

This work was supported by the Natural Science and Research Council of Canada.

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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of PhysiologyUniversity of AlbertaEdmontonCanada
  2. 2.Departmento de Neurobiología Celular Y Molecular, Instituto de Neurobiología, Campus JuriquillaUniversidad Nacional, Autónoma de MexicoQuerétaroMexico

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