Endocrine

, 40:137

Salivary Cortisol in Obstructive Sleep Apnea: The Effect of CPAP

  • Hershel Raff
  • Sandra L. Ettema
  • Daniel C. Eastwood
  • B. Tucker Woodson
Research Letter

References

  1. 1.
    G. Carneiro, S.M. Togeiro, L.F. Hayashi, F.F. Ribeiro-Filho, A.B. Ribeiro, S. Tufik, M.T. Zanella, Effect of continuous positive airway pressure therapy on hypothalamic-pituitary-adrenal axis function and 24-h blood pressure profile in obese men with obstructive sleep apnea syndrome. Am. J. Physiol. Endocrinol. Metab. 295, E380–E384 (2008)PubMedCrossRefGoogle Scholar
  2. 2.
    N. Meston, R.J.O. Davies, R. Mullins, C. Jenkinson, J.A. Wass, J.R. Stradling, Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnea. J. Int. Med. 254, 447–454 (2003)CrossRefGoogle Scholar
  3. 3.
    H. Raff, Utility of salivary cortisol measurements in Cushing’s syndrome and adrenal insufficiency. J. Clin. Endocrinol. Metab. 94, 3647–3655 (2009)PubMedCrossRefGoogle Scholar
  4. 4.
    M.W. Johns, A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14, 540–549 (1991)PubMedGoogle Scholar
  5. 5.
    H. Raff, P. Homar, D.P. Skoner, New enzyme immunoassay for salivary cortisol. Clin. Chem. 49, 203–204 (2003)PubMedCrossRefGoogle Scholar
  6. 6.
    D.L. Steward, T.C. Huntley, B.T. Woodson, V. Surdulescu, Palate implants for obstructive sleep apnea: multi-institution, randomized, placebo-controlled study. Otolaryngol. Head Neck Surg. 139, 506–510 (2008)PubMedCrossRefGoogle Scholar
  7. 7.
    L.M. Tomfohr, S. Ancoli-Israel, J.S. Loredo, J.E. Dimsdale, Effects of continuous positive airway pressure on fatigue and sleepiness in patients with obstructive sleep apnea: data from a randomized controlled trial. Sleep 34, 121–126 (2011)PubMedGoogle Scholar
  8. 8.
    A.N. Vgontzas, S. Pejovic, E. Zoumakis, H.M. Lin, C.M. Bentley, E.O. Bixler, A. Sarrigiannidis, M. Basta, G.P. Chrousos, Hypothalamic-pituitary-adrenal axis activity in obese men with and without sleep apnea: Effects of continuous positive airway pressure therapy. J. Clin. Endocrinol. Metab. 92, 4199–4207 (2007)PubMedCrossRefGoogle Scholar
  9. 9.
    A. Schmoller, F. Eberhardt, K. Jauch-Chara, U. Schweiger, P. Zabel, A. Peters, B. Schultes, K.M. Oltmanns, Continuous positive airway pressure therapy decreases evening cortisol concentrations in patients with severe obstructive sleep apnea. Metab. Clin. Exp. 58, 848–853 (2009)PubMedGoogle Scholar
  10. 10.
    F. Dadoun, P. Darmon, V. Achard, S. Boullu-Ciocca, F. Philip-Joet, M.C. Alessi, M. Rey, M. Grino, A. Dutour, Effect of sleep apnea syndrome on the circadian profile of cortisol in obese men. Am. J. Physiol. Endocrinol. Metab. 293, E466–E474 (2007)PubMedCrossRefGoogle Scholar
  11. 11.
    A.N. Vgontzas, E.O. Bixler, H.-M. Lin, P. Prolo, Vela.-Bueno.A. Mastorakos, A. Kales, G.P. Chrousos, Chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis: clinical implications. J. Clin. Endocrinol. Metab. 86, 2787–2794 (2001)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Hershel Raff
    • 1
    • 2
  • Sandra L. Ettema
    • 3
  • Daniel C. Eastwood
    • 4
  • B. Tucker Woodson
    • 5
  1. 1.Endocrine Research LaboratoryAurora St. Luke’s Medical CenterMilwaukeeUSA
  2. 2.Division of Endocrinology, Metabolism, and Clinical NutritionMedical College of WisconsinMilwaukeeUSA
  3. 3.Division of Otolaryngology/Head and Neck SurgerySouthern Illinois University School of MedicineSpringfieldUSA
  4. 4.Division of Biostatistics, Institute for Health and SocietyMedical College of WisconsinMilwaukeeUSA
  5. 5.Division of Sleep Medicine, Department of Otolaryngology and Communication SciencesMedical College of WisconsinMilwaukeeUSA

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