Comprehensive Therapy

, Volume 33, Issue 1, pp 18–20 | Cite as

Wolfram Syndrome: Case Report and Review of the Literature

  • Şeyhmus Ari
  • Uğur Keklíkçí
  • İhsan Çaça
  • Kaan Ünlü
  • Hasan Kayabaşi
Original Article
First Online:
Received:
Accepted:

Wolfram syndrome (WFS) is a rare diffuse neurodegenerative disorder characterized by diabetes insipidus, diabetes mellitus, optic atrophy, deafness, and a wide variety of central nervous system abnormalities. Insulin-dependent diabetes mellitus with optic nerve atrophy is a sufficient criterion for the diagnosis. WFS is a devastating disease for the patients and their families. This study emphasizes the need for careful evaluation of cases having insulin-dependent diabetes mellitus and optic atrophy.

Keywords

Diabetic Retinopathy Diabetes Insipidus Sensorineural Hearing Loss Optic Atrophy Central Diabetes Insipidus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© The American Society of Contempary Medicine and Surgery 2007

Authors and Affiliations

  • Şeyhmus Ari
    • 1
    • 4
  • Uğur Keklíkçí
    • 2
  • İhsan Çaça
    • 2
  • Kaan Ünlü
    • 2
  • Hasan Kayabaşi
    • 3
  1. 1.Department of OphthalmologyDiyarbakır State HospitalDiyarbakırTurkey
  2. 2.Department of OphthalmologyDicle University Faculty of MedicineDiyarbakırTurkey
  3. 3.Department of Internal MedicineDicle University Faculty of MedicineDiyarbakırTurkey
  4. 4.Diyarbakır Devlet HastanesiDiyarbakırTurkey

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