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Obstructive sleep apnea: An unrecognized but prevalent condition

  • Original Article
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Comprehensive Therapy

Abstract

Obstructive sleep apnea remains an unrecognized and under appreciated disease. The reported prevalence ranges from 2% to 10%. Risk factors include obesity, increased neck circumference, and certain ethnic groups. An apnea index >20 is associated with higher mortality rate.

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References

  1. Polysomnography Task Force, American Sleep Disorders Association Standards of Practice Committee. Practice parameters for the indications for polysomnography and related procedures. Sleep. 1997;20:406–422.

    Google Scholar 

  2. Johns MW. Reliability and factor analysis of the Epworth sleepiness scale. Sleep. 1992;15:376–381.

    PubMed  CAS  Google Scholar 

  3. Ferguson KA, Ono T, Lowe AA, Ryan CF, Fleetham JA. The relationship between obesity and craniofacial structure in obstructive sleep apnea. Chest. 1995;108:375–381.

    PubMed  CAS  Google Scholar 

  4. He J, Kryger MH, Zorick FJ, Conway W, Roth T. Mortality and apnea index in obstructive sleep apnea. Experience in 385 male patients. Chest. 1988;94:9–14.

    PubMed  CAS  Google Scholar 

  5. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993;328:1230–1235.

    Article  PubMed  CAS  Google Scholar 

  6. Kripke DF, Ancoli-Israel S, Klauber MR, Wingard DL, Mason WJ, Mullaney DJ. Prevalence of sleep-disordered breathing in ages 40–64 years: a population-based survey. Sleep. 1997;20:65–76.

    PubMed  CAS  Google Scholar 

  7. Ancoli-Israel S, Kripke DF, Klauber MR, Mason WJ, Fell R, Kaplan O. Sleep-disordered breathing in community-dwelling elderly. Sleep. 1991;14:486–495.

    PubMed  CAS  Google Scholar 

  8. Bradley TD, Brown IG, Grossman RF, et al. Pharyngeal size in snorers, nonsnorers, and patients with obstructive sleep apnea. N Engl J Med. 1986;315:1327–1331.

    Article  PubMed  CAS  Google Scholar 

  9. Millman RP, Redline S, Carlisle CC, Assaf AR, Levinson PD. Daytime hypertension in obstructive sleep apnea. Prevalence and contributing risk factors. Chest. 1991;99: 861–866.

    PubMed  CAS  Google Scholar 

  10. Williams AJ, Houston D, Finberg S, Lam C, Kinney JL, Santiago S. Sleep apnea syndrome and essential hypertension. Am J Cardiol. 1985;55:1019–1022.

    Article  PubMed  CAS  Google Scholar 

  11. Fletcher EC, DeBehnke RD, Lovoi MS, Gorin AB. Undiagnosed sleep apnea in patients with essential hypertension. Ann Intern Med. 1985;103:190–195.

    PubMed  CAS  Google Scholar 

  12. Hla KM, Young TB, Bidwell T, Palta M, Skatrud JB, Dempsey J. Sleep apnea and hypertension. A population-based study. Ann Intern Med. 1994;120:382–388.

    PubMed  CAS  Google Scholar 

  13. Miller WP. Cardiac arrhythmias and conduction disturbances in the sleep apnea syndrome. Prevalence and significance. Am J Med. 1982;73:317–321.

    Article  PubMed  CAS  Google Scholar 

  14. Shepard JW Jr, Garrison MW, Grither DA, Evans R, Schweitzer PK. Relationship of ventricular ectopy to nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease. Am J Med. 1985;78:28–34.

    Article  PubMed  Google Scholar 

  15. Guilleminault C, Connolly SJ, Winkle RA. Cardiac arrhythmia and conduction disturbances during sleep in 400 patients with sleep apnea syndrome. Am J Cardiol. 1983;52: 490–494.

    Article  PubMed  CAS  Google Scholar 

  16. Hanly P, Sasson Z, Zuberi N, Lunn K. ST-segment depression during sleep in obstructive sleep apnea [see comments]. Am J Cardiol. 1993;71:1341–1345.

    Article  PubMed  CAS  Google Scholar 

  17. Mooe T, Rabben T, Wiklund U, Franklin KA, Eriksson P. Sleep-disordered breathing in men with coronary artery disease. Chest. 1996;109:659–663.

    PubMed  CAS  Google Scholar 

  18. Hung J, Whitford EG, Parsons RW, Hillman DR. Association of sleep apnoea with myocardial infarction in men. Lancet. 1990;336:261–264.

    Article  PubMed  CAS  Google Scholar 

  19. Smith PL, Gold AR, Meyers DA, Haponik EF, Bleecker ER. Weight loss in mildly to moderately obese patients with obstructive sleep apnea. Ann Intern Med. 1985;103(6 Pt 1):850–855.

    PubMed  CAS  Google Scholar 

  20. Rosenow F, McCarthy V, Caruso AC. Sleep apnoea in endocrine diseases. J Sleep Res. 1998;7:3–11.

    Article  PubMed  CAS  Google Scholar 

  21. Meslier N, Giraud P, Person C, Badatcheff Å, Racineux JL. Prevalence of hypothyroidism in sleep apnoea syndrome. Eur J Med. 1992;1:437–438.

    PubMed  CAS  Google Scholar 

  22. Rajagopal KR, Abbrecht PH, Derderian SS, et al. Obstructive sleep apnea in hypothyroidism. Ann Intern Med. 1984; 101:491–494.

    PubMed  CAS  Google Scholar 

  23. Pretl M, Weiss V, Sonka K. [The sleep apnea syndrome in patients with acromegaly]. Vnitr Lek. 1995;41:53–55.

    PubMed  CAS  Google Scholar 

  24. Chaouat A, Weitzenblum E, Krieger J, Ifoundza T, Oswald M, Kessler R. Association of chronic obstructive pulmonary disease and sleep apnea syndrome. Am J Respir Crit Care Med. 1995;151:82–86.

    PubMed  CAS  Google Scholar 

  25. Weitzenblum E, Chaouat A, Charpentier C, et al. Sleep-related hypoxaemia in chronic obstructive pulmonary disease: causes, consequences and treatment. Respiration. 1997; 64:187–193.

    Article  PubMed  CAS  Google Scholar 

  26. Ahmed Q, Chung-Park M, Tomashefski JF, Jr. Cardiopulmonary pathology in patients with sleep apnea/obesity hypoventilation syndrome. Hum Pathol. 1997;28:264–269.

    Article  PubMed  CAS  Google Scholar 

  27. Partinen M, Jamieson A, Guilleminault C. Long-term outcome for obstructive sleep apnea syndrome patients. Mortality. Chest. 1988;94:1200–1204.

    PubMed  CAS  Google Scholar 

  28. Palomaki H, Partinen M, Juvela S, Kaste M. Snoring as a risk factor for sleep-related brain infarction. Stroke. 1989;20: 1311–1315.

    PubMed  CAS  Google Scholar 

  29. Jennum P, Borgesen SE. Intracranial pressure and obstructive sleep apnea. Chest. 1989;95:279–283.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. American Board of Sleep Medicine, Marshall University School of Medicine, Huntington, WV

    Imran T. Khawaja MD, FACP, FCCP (Diplomat, Associate Professor of Medicine)

  2. Pulmonary Critical Care & Sleep Medicine Section, Marshall University School of Medicine, Huntington, WV

    Imran T. Khawaja MD, FACP, FCCP (Diplomat, Associate Professor of Medicine)

  3. Internal Medicine, Marshall University School of Medicine, Huntington, WV

    Rameez T. Sayyed MD (Resident)

  4. Pulmonary Medicine, Marshall University School of Medicine, Huntington, WV

    Hani Jaouni MD (Fellow)

Authors
  1. Imran T. Khawaja MD, FACP, FCCP
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  2. Rameez T. Sayyed MD
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  3. Hani Jaouni MD
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Khawaja, I.T., Sayyed, R.T. & Jaouni, H. Obstructive sleep apnea: An unrecognized but prevalent condition. Compr Ther 26, 294–297 (2000). https://doi.org/10.1007/s12019-000-0032-7

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  • DOI: https://doi.org/10.1007/s12019-000-0032-7

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