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Clinical Reviews in Allergy & Immunology

, Volume 56, Issue 1, pp 86–98 | Cite as

Contact Dermatitis in Atopic Dermatitis Children—Past, Present, and Future

  • Jenna Borok
  • Catalina Matiz
  • Alina Goldenberg
  • Sharon E. JacobEmail author
Article
  • 238 Downloads

Abstract

Allergic contact dermatitis (ACD) used to be considered a rarity in children, but recently has been estimated to effect 4.4 million children in the USA alone, with a notable rise in investigative research in the field of pediatric ACD. Researchers have shown that patch testing is safe and effective in afflicted children and that those with atopic dermatitis (AD) have similar sensitization rates, although they have a higher sensitization to certain allergens, thought to be related to the inflammatory (IL-4) milieu. Patch testing assessment guidelines in children include five key considerations: if a patient’s dermatitis worsens, changes distribution, fails to improve with topical therapy, or immediately rebounds after removal of topical treatments; if a patient has a particular distribution of dermatitis; if a working patient has hand eczema that fails to improve with therapy; if the patient has AD that started in adolescence or adulthood with definitely no history of childhood eczema; and importantly, if a patient has severe or widespread atopic dermatitis that will require immunosuppressive systemic medication.

Keywords

Pediatric Allergic contact dermatitis Atopic dermatitis Sensitization Review 

Abbreviations

CD

Contact dermatitis

ICD

Irritant contact dermatitis

ACD

Allergic contact dermatitis

PPTR

Positive patch test reaction

AD

Atopic dermatitis

RPPT

Relevant positive patch test

NACDG

The North American Contact Dermatitis Group

PCDR

The Pediatric Contact Dermatitis Registry

TEWL

Transepidermal water loss

E.A.S.I.

Eczema area and severity index

AOY

Allergen of the Year

TCS

topical corticosteroids

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Jenna Borok
    • 1
  • Catalina Matiz
    • 2
  • Alina Goldenberg
    • 3
  • Sharon E. Jacob
    • 4
    Email author
  1. 1.The Mount Sinai HospitalNew YorkUSA
  2. 2.Southern California Permanente Medical GroupSan DiegoUSA
  3. 3.Department of DermatologyUniversity of California San DiegoSan DiegoUSA
  4. 4.Department of DermatologyLoma Linda UniversityLoma LindaUSA

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