Stem Cell Reviews and Reports

, Volume 10, Issue 5, pp 663–670

Application of iPS Cells in Dental Bioengineering and Beyond


DOI: 10.1007/s12015-014-9531-2

Cite this article as:
Liu, P., Zhang, Y., Chen, S. et al. Stem Cell Rev and Rep (2014) 10: 663. doi:10.1007/s12015-014-9531-2


The stem-cell-based tissue-engineering approaches are widely applied in establishing functional organs and tissues for regenerative medicine. Successful generation of induced pluripotent stem cells (iPS cells) and rapid progress of related technical platform provide great promise in the development of regenerative medicine, including organ regeneration. We have previously reported that iPS cells could be an appealing stem cells source contributing to tooth regeneration. In the present paper, we mainly review the application of iPS technology in dental bioengineering and discuss the challenges for iPS cells in the whole tooth regeneration.


iPS cells Dental bioengineering Tooth regeneration 

Supplementary material

12015_2014_9531_MOESM1_ESM.pdf (1.4 mb)
ESM 1(PDF 1471 kb)
12015_2014_9531_MOESM2_ESM.pdf (640 kb)
ESM 2(PDF 639 kb)

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cell Biology and Regenerative MedicineSouth China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of SciencesGuangzhouPeople’s Republic of China
  2. 2.Department of Regeneration Medicine, School of Pharmaceutical ScienceJilin UniversityChangchunPeople’s Republic of China

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