Cell Biochemistry and Biophysics

, Volume 67, Issue 3, pp 1029–1032 | Cite as

A Resting-State Functional Magnetic Resonance Imaging Study of Acute Carbon Monoxide Poisoning in Humans

Original Paper


The objective of this study was to evaluate the brain function characteristics of carbon monoxide poisoning patients using resting-state functional magnetic resonance imaging (fMRI) method. For this purpose, 12 carbon monoxide poisoning patients and healthy controls were subjected to resting-state fMRI scans separately. A regional homogeneity (ReHo) approach was used to analyze the brain function in carbon monoxide poisoning patients. Compared with control group, the value of ReHo in carbon monoxide poisoning group showed distinct decrease in bilateral superior frontal gyrus, middle frontal gyrus, right cuneus, left middle temporal gyrus, right insula, and cerebellum. Therefore, it was concluded that the brain functions in carbon monoxide poisoning patients were abnormal under the resting-state. The cuneate lobe function may indicate the degree of brain hypoxia and strengthening the cerebellar function training may promote the rehabilitation process.


Acute carbon monoxide poisoning Magnetic resonance imaging Resting-state Regional homogeneity 


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Liu Dinghua
    • 1
  • Liu Dongbo
    • 1
  • Zhang Jianyu
    • 1
  • Peng Lan
    • 1
  1. 1.Department of NeurologyAffiliated Jiangyin Hospital of Southeast University Medical CollegeJiangyinChina

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