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Cell Biochemistry and Biophysics

, Volume 66, Issue 2, pp 347–350 | Cite as

Changes of Sleep Adaptation in Hospitalized Patients with Depression

  • Shasha Song
  • Zhi GengEmail author
  • Shutao Zhai
  • Jie Xu
  • Gang Hou
  • Xinbao Zhang
Translational Biomedical Research

Abstract

Sleep adaptation in an unfamiliar environment, the so-called “first-night effect”, is known to occur in healthy individuals. To avoid the confounding effects of the “first-night effect”, the first-night sleep data are not used in most of sleep studies. In the present study, we examined changes of sleep adaptation in hospitalized patients with depression. Polysomnographic recordings were obtained for two consecutive nights from 14 patients, and sleep parameters were compared between both nights. Total sleep time, sleep latency, awakening times, movement awakening time, sleep efficiency, sleep architecture, rapid eye movement (REM) sleep latency, REM intensity, REM density, REM time, REM cycles, and other indicators showed no significant difference (p > 0.05) between the first and second nights. To conclude, hospitalized patients with depression have relatively less change in sleep adaptation, thus, the data from their first night do not need to be discarded.

Keywords

Depression Polysomnography Sleep disorders First- night effect Sleep adaptation 

References

  1. 1.
    Zimmerman, C., & Pfeiffer, H. (2007). Sleep disorders in depression: suggestions for a therapeutic approach. Nervenarzt, 78, 21–30.CrossRefGoogle Scholar
  2. 2.
    Arana-Lechuga, Y., Nunez-Ortiz, R., Teran-Perez, G., Castillo-Montoya, C., Jimenez-Anguiano, A., Gonzalez-Robles, R. O., et al. (2008). Sleep-EEG patterns of school children suffering from symptoms of depression compared to healthy controls. The World Journal of Biological Psychiatry, 9, 115–120.PubMedCrossRefGoogle Scholar
  3. 3.
    Benca, R. M., Obermeyer, W. H., Thisted, R. A., & Gillin, J. C. (1992). Sleep and psychiatric disorders. A meta-analysis. Archives of General Psychiatry, 49, 651–668.PubMedCrossRefGoogle Scholar
  4. 4.
    Jindal, R. D. (2009). Insomnia in patients with depression: some pathophysiological and treatment considerations. CNS Drugs, 2009(23), 309–329.CrossRefGoogle Scholar
  5. 5.
    Suetsugi, M., Mizuki, Y., Yamamoto, K., Uchida, S., & Watanabe, Y. (2007). The effect of placebo administration on the first-night effect in healthy young volunteers. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 31, 839–847.PubMedCrossRefGoogle Scholar
  6. 6.
    Le Bon, O., Staner, L., Hoffmann, G., Dramaix, M., San Sebastina, I., Murphy, J. R., et al. (2001). The first-night effect may last more than one night. Journal of Psychiatric Research, 35, 165–172.PubMedCrossRefGoogle Scholar
  7. 7.
    Mendels, J., & Hawkins, D. R. (1967). Sleep laboratory adaptation in normal subjects and depressed patients (“first night effect”). Electroencephalography and Clinical Neurophysiology, 22, 556–558.PubMedCrossRefGoogle Scholar
  8. 8.
    Kupfer, D. J., Weiss, B. L., Detre, T. P., & Foster, F. G. (1974). First night effect revisited: a clinical note. The Journal of Nervous and Mental Disease, 159, 205–209.PubMedCrossRefGoogle Scholar
  9. 9.
    Chinese Medical Association and Nanjing Medical University. (1995). Chinese classification of mental disorders (2nd ed.). Nanjing: Dong Nan University Press. (in Chinese).Google Scholar
  10. 10.
    Rechtschaffen, A., & Kales, A. (1968). A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects (pp. 1–13). California: Brain Information Service/Brain Research Institute of University of California.Google Scholar
  11. 11.
    Zhang, Y., Liu, X., Liu, X., et al. (1986). A polysomnographic study of primary depression. Chinese Journal of Nervous and Mental Disease, 12, 302–331. [Chinese].Google Scholar
  12. 12.
    Geng, Z., Xu, J., Zhai, S., et al. (1997). The first night effect of the new environment on the sleep in normal persons. Journal of Clinical Psychology Medicine, 7, 338–339. [Chinese].Google Scholar
  13. 13.
    Reynolds, C. F., I. I. I. (1987). Sleep and affective disorders. A minireview. Psychiatric Clinics of North America, 10, 583–591.PubMedGoogle Scholar
  14. 14.
    Reynolds, C. F., I. I. I., Newton, T. F., Shaw, D. H., Coble, P. A., & Kupfer, D. J. (1982). Electroencephalographic sleep findings in depressed outpatients. Psychiatry Research, 6, 65–75.PubMedCrossRefGoogle Scholar
  15. 15.
    Reynolds, C. F., I. I. I., Shaw, D. H., Newton, T. F., Coble, P. A., & Kupfer, D. J. (1983). EEG sleep in outpatients with generalized anxiety: a preliminary comparison with depressed outpatients. Psychiatry Research, 8, 81–89.PubMedCrossRefGoogle Scholar
  16. 16.
    Ansseau, M., Kupfer, D. J., Reynolds, C. F., I. I. I., & Coble, P. A. (1985). “Paradoxical” shortening of REM latency on first recording night in major depressive disorder: clinical and polysomnographic correlates. Biological Psychiatry, 20, 135–145.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Shasha Song
    • 1
  • Zhi Geng
    • 1
    Email author
  • Shutao Zhai
    • 2
  • Jie Xu
    • 2
  • Gang Hou
    • 3
  • Xinbao Zhang
    • 3
  1. 1.Department of NeurologyThe Sixth People’s Hospital affiliated with Shanghai Jiaotong UniversityShanghaiPeople’s Republic of China
  2. 2.Department of NeurophysiologyThe Affiliated Brain Hospital of Nanjing Medical UniversityNanjingPeople’s Republic of China
  3. 3.Department of PsychiatryThe Affiliated Brain Hospital of Nanjing Medical UniversityNanjingPeople’s Republic of China

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