Cardiovascular Toxicology

, Volume 7, Issue 2, pp 72–74

Cardiac safety of liposomal anthracyclines

Article

DOI: 10.1007/s12012-007-0014-4

Cite this article as:
Batist, G. Cardiovasc Toxicol (2007) 7: 72. doi:10.1007/s12012-007-0014-4

Abstract

Anthracyclines remain amongst the most active therapeutic agents for breast cancer treatment. Rather than being supplanted by novel targeted agents, they are being combined with them in various schedules. Furthermore, anthracyclines themselves are still being studied, with increasing biological understanding of their biological activity and molecular targets. A cardiac safe formulation of doxorubicin opens a number of interesting therapeutic opportunities. Liposomal doxorubicins appear to provide this opportunity.

Keywords

Myocet Pegylated liposomal doxorubicin Trastuzumab Cardiotoxicity 

Copyright information

© Humana Press Inc. 2007

Authors and Affiliations

  1. 1.The Montreal Center for Experimental Therapeutics in Cancer, Lady Davis Institute for Medical Research, The Sir Mortimer B Davis-Jewish General HospitalMcGill UniversityMontrealCanada

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