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Biological Trace Element Research

, Volume 186, Issue 1, pp 279–287 | Cite as

Ameliorative Effects of Selenium in ZnO NP-Induced Oxidative Stress and Hematological Alterations in Catla catla

  • Muhammad Saleem Asghar
  • Naureen Aziz Qureshi
  • Farhat Jabeen
  • Muhammad Saleem Khan
  • Muhammad Shakeel
  • Abdul Shakoor Chaudhry
Article

Abstract

Various applications of zinc oxide nanoparticles (ZnO NPs) can increase pollution in aquatic environments. Consequently, pollution can cause toxicity in fish as indicated by oxidative stress, hematotoxicity, and changes in gill and liver histology. Selenium is known for its antioxidant potential in scavenging the free radicals generated during ZnO NP-induced oxidative stress. This study tested the ameliorative role of selenium against ZnO NP-induced toxicity in freshwater fish Catla catla. Four groups of replicated fish, representing control, selenium-treated, ZnO NP-treated, and ZnO NPs+selenium-treated, were used in this study. The ZnO NPs (40 mg l−1) were given to fish in water whereas selenium (50 μg kg−1) was given as sodium selenite in feed. After 28 days of exposure, the fish specimens were processed to collect samples of blood, gills, and liver. The results demonstrated that the consumption of selenium containing feeds protected the C. catla from ZnO NP-induced toxicity and oxidative stress. The use of selenium containing feeds appeared to have reduced the contents of glutathione S-transferase (GST) and glutathione reduced (GSH), and increased the level of catalase (CAT) and superoxide dismutase (SOD). Furthermore, the consumption of selenium in feeds improved the hematological parameters in ZnO NP-treated fish. This study suggests that dietary selenium might be able to ameliorate ZnO NP-induced toxicity in fish.

Keywords

Catla catla Nanoparticles Protection Selenium Toxicity ZnO 

Notes

Acknowledgments

The authors are very thankful to the Department of Zoology Government College University Faisalabad, Pakistan, for providing the laboratory facilities and technical support for the completion of this research.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in this study involving vertebrates like fish were approved by the research ethical committee and the animal care and use committee of the Government College University Faisalabad, Pakistan.

References

  1. 1.
    Ilyas R, Javed M (2013) Acute toxicity of endosulfan to the fish species Catla catla, Cirrhina mrigala and Labeo rohita. Int J Agric Biol 15(1):149–152Google Scholar
  2. 2.
    Khan MS, Jabeen F, Asghar MS, Qureshi NA, Shakeel M, Noureen A, Shabbir S (2015) Role of nao-ceria in the amelioration of oxidative stress: current and future applications in medicine. Int J Biosci 6(8):89–109.  https://doi.org/10.12692/ijb/6.8.89-109 CrossRefGoogle Scholar
  3. 3.
    Hamid A, Khan MU, Yaqoob J, Umar A, Rehman A, Javed S, Sohail A, Anwar A, Khan MS, Ali A (2016) Assessment of mercury load in river Ravi, urban sewage streams of Lahore Pakistan and its impact on the oxidative stress of exposed fish. J Bio Environ Sci 8(4):63–72Google Scholar
  4. 4.
    Khan MS, Qureshi NA, Jabeen F, Shakeel M, Asghar MS (2017) Assessment of waterborne amine-coated silver nanoparticle (ag-NP)-induced toxicity in Labeo rohita by histological and hematological profiles. Biol Trace Elem Res 182:1–10.  https://doi.org/10.1007/s12011-017-1080-5 CrossRefGoogle Scholar
  5. 5.
    Begum A, Harikrishna S, Khan I (2009) Analysis of heavy metals in water, sediments and fish samples of Madivala lakes of Bangalore, Karnataka. Int J ChemTech Res 1(2):245–249Google Scholar
  6. 6.
    Umar A, Sohail A, Javed S, Yaqoob J, Hamid A, Arshad T, Khalid M, Khan MU, Khan MS (2016) Biosorption of some toxic metals by pine nut shell from contaminated waste water. J Bio Environ Sci 9(1):465–473Google Scholar
  7. 7.
    Brun NR, Lenz M, Wehrli B, Fent K (2014) Comparative effects of zinc oxide nanoparticles and dissolved zinc on zebrafish embryos and eleuthero-embryos: importance of zinc ions. Sci Total Environ 476:657–666.  https://doi.org/10.1016/j.scitotenv.2014.01.053 CrossRefPubMedGoogle Scholar
  8. 8.
    Asghar MS, Qureshi NA, Jabeen F, Khan MS, Shakeel M, Noureen A (2015) Toxicity of zinc nanoparticles in fish: a critical review. J Bio Environ Sci 7(1):431–439Google Scholar
  9. 9.
    Buerki-Thurnherr T, Xiao L, Diener L, Arslan O, Hirsch C, Maeder-Althaus X, Grieder K, Wampfler B, Mathur S, Wick P (2012) In vitro mechanistic study towards a better understanding of ZnO nanoparticle toxicity. Nanotoxicol 7(4):402–416.  https://doi.org/10.3109/17435390.2012.666575 CrossRefGoogle Scholar
  10. 10.
    Blinova I, Ivask A, Heinlaan M, Mortimer M, Kahru A (2010) Ecotoxicity of nanoparticles of CuO and ZnO in natural water. Environ Pollut 158(1):41–47.  https://doi.org/10.1016/j.envpol.2009.08.017 CrossRefPubMedGoogle Scholar
  11. 11.
    Franklin NM, Rogers NJ, Apte SC, Batley GE, Gadd GE, Casey PS (2007) Comparative toxicity of nanoparticulate ZnO, bulk ZnO, and ZnCl2 to a freshwater microalga (Pseudokirchneriella subcapitata): the importance of particle solubility. Environ Sci Technol 41(24):8484–8490.  https://doi.org/10.1021/es071445r CrossRefPubMedGoogle Scholar
  12. 12.
    Kao Y-Y, Chen Y-C, Cheng T-J, Chiung Y-M, Liu P-S (2012) Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity. Toxicol Sci 125(2):462–472CrossRefGoogle Scholar
  13. 13.
    Heng BC, Zhao X, Xiong S, Ng KW, Boey FY-C, Loo JS-C (2010) Toxicity of zinc oxide (ZnO) nanoparticles on human bronchial epithelial cells (BEAS-2B) is accentuated by oxidative stress. Food Chem Toxicol 48(6):1762–1766CrossRefGoogle Scholar
  14. 14.
    Nel A, Xia T, Mädler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311(5761):622–627.  https://doi.org/10.1126/science.1114397 CrossRefGoogle Scholar
  15. 15.
    Sharma P, Jha AB, Dubey RS, Pessarakli M (2012) Reactive oxygen species, oxidative damage, and antioxidative defense mechanism in plants under stressful conditions. J Bot 2012:1–26CrossRefGoogle Scholar
  16. 16.
    Song W, Zhang J, Guo J, Zhang J, Ding F, Li L, Sun Z (2010) Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles. Toxicol Lett 199(3):389–397CrossRefGoogle Scholar
  17. 17.
    Zhu D, Hu C, Sheng W, Tan K, Haidekker M, Sun A, Sun G, Lee J (2009) NAD (P) H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2. Biochem J 421:201–210CrossRefGoogle Scholar
  18. 18.
    Valko M, Rhodes C, Moncol J, Izakovic M, Mazur M (2006) Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 160(1):1–40CrossRefGoogle Scholar
  19. 19.
    Brewer NT, Fazekas KI (2007) Predictors of HPV vaccine acceptability: a theory-informed, systematic review. Prev Med 45(2):107–114CrossRefGoogle Scholar
  20. 20.
    Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH (2002) Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4. J Pharm Exp Ther 302(3):881–888CrossRefGoogle Scholar
  21. 21.
    Klaunig JE, Kamendulis LM, Hocevar BA (2010) Oxidative stress and oxidative damage in carcinogenesis. Toxicol Pathol 38(1):96–109CrossRefGoogle Scholar
  22. 22.
    Asghar MS, Quershi NA, Jabeen F, Shakeel M, Khan MS (2016) Genotoxicity and oxidative stress analysis in the Catla catla treated with ZnO NPs. J Bio Environ Sci 8(4):91–104Google Scholar
  23. 23.
    Seifried HE, Anderson DE, Fisher EI, Milner JA (2007) A review of the interaction among dietary antioxidants and reactive oxygen species. J Nutr Biochem 18(9):567–579CrossRefGoogle Scholar
  24. 24.
    Khan MS, Qureshi NA, Jabeen F (2017) Assessment of toxicity in fresh water fish Labeo rohita treated with silver nanoparticles. App Nanosci 7:1–13.  https://doi.org/10.1007/s13204-017-0559-x CrossRefGoogle Scholar
  25. 25.
    Ramoutar RR, Brumaghim JL (2007) Effects of inorganic selenium compounds on oxidative DNA damage. J Inorg Biochem 101(7):1028–1035CrossRefGoogle Scholar
  26. 26.
    Battin EE, Brumaghim JL (2009) Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms. Cell Biochem Biophys 55(1):1–23CrossRefGoogle Scholar
  27. 27.
    Perron NR, Hodges JN, Jenkins M, Brumaghim JL (2008) Predicting how polyphenol antioxidants prevent DNA damage by binding to iron. Inorg Chem 47(14):6153–6161CrossRefGoogle Scholar
  28. 28.
    Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guigó R, Gladyshev VN (2003) Characterization of mammalian selenoproteomes. Science 300(5624):1439–1443CrossRefGoogle Scholar
  29. 29.
    Collins CA, Fry FH, Holme AL, Yiakouvaki A, Al-Qenaei A, Pourzand C, Jacob C (2005) Towards multifunctional antioxidants: synthesis, electrochemistry, in vitro and cell culture evaluation of compounds with ligand/catalytic properties. Org Biomol Chem 3(8):1541–1546CrossRefGoogle Scholar
  30. 30.
    Schram E, Pedrero Z, Cámara C, Van Der Heul JW, Luten JB (2008) Enrichment of African catfish with functional selenium originating from garlic. Aquac Res 39(8):850–860CrossRefGoogle Scholar
  31. 31.
    Abdel-Tawwab M, Mousa MA, Abbass FE (2007) Growth performance and physiological response of African catfish, Clarias gariepinus (B.) fed organic selenium prior to the exposure to environmental copper toxicity. Aquaculture 272(1):335–345CrossRefGoogle Scholar
  32. 32.
    Lin Y-H, Shiau S-Y (2007) The effects of dietary selenium on the oxidative stress of grouper, Epinephelus malabaricus, fed high copper. Aquaculture 267(1):38–43CrossRefGoogle Scholar
  33. 33.
    Lapchak PA, Zivin JA (2003) Ebselen, a seleno-organic antioxidant, is neuroprotective after embolic strokes in rabbits synergism with low-dose tissue plasminogen activator. Stroke 34(8):2013–2018CrossRefGoogle Scholar
  34. 34.
    Koestner JA, Nelson LD, Morris JRJA, Safcsak K (1990) Use of recombinant human erythropoietin (r-HuEPO) in a Jehovah’s Witness refusing transfusion of blood products: case report. J Trauma Acute Care Surg 30(11):1406–1408.  https://doi.org/10.1097/00005373-199011000-00016 CrossRefGoogle Scholar
  35. 35.
    Borensztein E, De Gregorio J, Lee J-W (1998) How does foreign direct investment affect economic growth? J Int Econ 45(1):115–135.  https://doi.org/10.3386/w5057 CrossRefGoogle Scholar
  36. 36.
    Singn N, Mccoy M, Tice R, Schneider E (1988) A simple technique for quantification of low levels of DNA damage in individual cells. Exp Cell Res 175:184–191.  https://doi.org/10.1016/0014-4827(88)90265-0 CrossRefGoogle Scholar
  37. 37.
    Payá M, Halliwell B, Hoult J (1992) Interactions of a series of coumarins with reactive oxygen species: scavenging of superoxide, hypochlorous acid and hydroxyl radicals. Biochem Pharmacol 44(2):205–214.  https://doi.org/10.1016/0006-2952(92)90002-z CrossRefPubMedGoogle Scholar
  38. 38.
    Peixoto AL, Pereira-Moura MVL (2008) A new genus of Monimiaceae from the Atlantic Coastal Forest in South-Eastern Brazil. Kew Bull 63(1):137–141CrossRefGoogle Scholar
  39. 39.
    Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione S-transferases the first enzymatic step in mercapturic acid formation. J Biol Chem 249(22):7130–7139Google Scholar
  40. 40.
    Jollow D, Mitchell J, Na Z, Gillette J (1974) Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3, 4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacol 11(3):151–169.  https://doi.org/10.1159/000136485 CrossRefGoogle Scholar
  41. 41.
    Aebi H (1984) [13] Catalase in vitro. Methods Enzymol 105:121–126CrossRefGoogle Scholar
  42. 42.
    Buege JA, Aust SD (1978) [30] Microsomal lipid peroxidation. Methods Enzymol 52:302–310CrossRefGoogle Scholar
  43. 43.
    Kołodziejczak-Radzimska A, Jesionowski T (2014) Zinc oxide—from synthesis to application: a review. Materials 7(4):2833–2881.  https://doi.org/10.3390/ma7042833 CrossRefPubMedPubMedCentralGoogle Scholar
  44. 44.
    Hong R, Pan T, Qian J, Li H (2006) Synthesis and surface modification of ZnO nanoparticles. Chem Engi J 119(2):71–81.  https://doi.org/10.1016/j.cej.2006.03.003 CrossRefGoogle Scholar
  45. 45.
    Kanipandian N, Thirumurugan R (2014) A feasible approach to phyto-mediated synthesis of silver nanoparticles using industrial crop Gossypium hirsutum (cotton) extract as stabilizing agent and assessment of its in vitro biomedical potential. Ind Crop Prod 55:1–10.  https://doi.org/10.1016/j.indcrop.2014.01.042 CrossRefGoogle Scholar
  46. 46.
    Abdullah M, Okuyama K (2004) Zinc oxide nanoparticles prepared by a simple heating: effect of polymer addition and polymer absence on the morphology. J Eng Technol Manage 36(2):141–153.  https://doi.org/10.5614/itbj.eng.sci.2004.36.2.3 CrossRefGoogle Scholar
  47. 47.
    Khan MS, Qureshi NA, Jabeen F, Asghar MS, Shakeel M, Fakhar -e -Alam M (2016b) Eco-friendly synthesis of silver nanoparticles through economical methods and assessment of toxicity through oxidative stress analysis in the Labeo Rohita. Biol Trace Elem Res: 1–13. doi:  https://doi.org/10.1007/s12011-016-0838-5, 176CrossRefGoogle Scholar
  48. 48.
    Kaya H, Aydın F, Gürkan M, Yılmaz S, Ates M, Demir V, Arslan Z (2015) Effects of zinc oxide nanoparticles on bioaccumulation and oxidative stress in different organs of tilapia (Oreochromis niloticus). Environ Toxicol Pharmacol 40(3):936–947CrossRefGoogle Scholar
  49. 49.
    Hao L, Chen L (2012) Oxidative stress responses in different organs of carp (Cyprinus carpio) with exposure to ZnO nanoparticles. Ecotoxicol Environ Saf 80:103–110CrossRefGoogle Scholar
  50. 50.
    Tinggi U (2008) Selenium: its role as antioxidant in human health. Environ Health Prev Med 13(2):102–108CrossRefGoogle Scholar
  51. 51.
    Mayo JC, Tan D-X, Sainz RM, Lopez-Burillo S, Reiter RJ (2003) Oxidative damage to catalase induced by peroxyl radicals: functional protection by melatonin and other antioxidants. Free Radic Res 37(5):543–553CrossRefGoogle Scholar
  52. 52.
    Biller-Takahashi JD, Takahashi LS, Mingatto FE, Urbinati EC (2015) The immune system is limited by oxidative stress: dietary selenium promotes optimal antioxidative status and greatest immune defense in pacu Piaractus mesopotamicus. Fish Shellfish Immunol 47(1):360–367CrossRefGoogle Scholar
  53. 53.
    Hoffmann F, Manning MJ (2014) Herbal medicine and botanical medical fads. RoutledgeGoogle Scholar
  54. 54.
    Ghneim HK, Al-Sheikh YA (2011) Effect of selenium supplementation on glutathione peroxidase and catalase activities in senescent cultured human fibroblasts. Ann Nutr Metab 59(2–4):127–138CrossRefGoogle Scholar
  55. 55.
    Masukawa T, Nishimura T, Iwata H (1984) Differential changes of glutathione S-transferase activity by dietary selenium. Biochem Pharmacol 33(16):2635–2639CrossRefGoogle Scholar
  56. 56.
    Dzobo K, Naik YS (2013) Effect of selenium on cadmium-induced oxidative stress and esterase activity in rat organs. S Afr J Sci 109(5–6):1–8CrossRefGoogle Scholar
  57. 57.
    El-Demerdash FM, Nasr HM (2014) Antioxidant effect of selenium on lipid peroxidation, hyperlipidemia and biochemical parameters in rats exposed to diazinon. J Trace Elem Med Biol 28(1):89–93CrossRefGoogle Scholar
  58. 58.
    Akil M, Bicer M, Menevse E, Baltaci A, Mogulkoc R (2010) Selenium supplementation prevents lipid peroxidation caused by arduous exercise in rat brain tissue. Bratisl Lek Listy 112(6):314–317Google Scholar
  59. 59.
    Khan MS, Jabeen F, Qureshi NA, Asghar, , M.S. S, M., , Noureen A (2015b) Toxicity of silver nanoparticles in fish: a critical review. J Bio Environ Sci 6(5): 211–227Google Scholar
  60. 60.
    Khan MU, Qurashi NA, Khan MS, Jabeen F, Umar A, Yaqoob J, Wajid M (2016) Generation of reactive oxygen species and their impact on the health related parameters: a critical review. Int J Biosci 9(1):303–323Google Scholar
  61. 61.
    Chang W-J, Joe K-T, Park H-Y, Jeong J-D, Lee D-H (2013) The relationship of liver function tests to mixed exposure to lead and organic solvents. Ann Occup Environ Med 25(1):5CrossRefGoogle Scholar
  62. 62.
    Bitiren M, Karakılçık AZ, Zerin M, Aksoy N, Musa D (2004) Effects of selenium on histopathological and enzymatic changes in experimental liver injury of rats. Exp Toxicol Pathol 56(1):59–64PubMedGoogle Scholar
  63. 63.
    El-Bayoumy K (2001) The protective role of selenium on genetic damage and on cancer. Mutat Res-Fundam Mol Mech Mutag 475(1):123–139CrossRefGoogle Scholar
  64. 64.
    Khalil W, Booles H (2011) Protective role of selenium against over-expression of cancer-related apoptotic genes induced by o-cresol in rats. Arch Ind Hyg Toxicol 62(2):121–129Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Muhammad Saleem Asghar
    • 1
  • Naureen Aziz Qureshi
    • 2
  • Farhat Jabeen
    • 1
  • Muhammad Saleem Khan
    • 1
  • Muhammad Shakeel
    • 1
  • Abdul Shakoor Chaudhry
    • 3
  1. 1.Department of ZoologyGovernment College University FaisalabadPakistan
  2. 2.Government College Women University FaisalabadPakistan
  3. 3.School of Natural and Environmental SciencesNewcastle UniversityNewcastle upon TyneUK

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