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Biological Trace Element Research

, Volume 181, Issue 1, pp 154–163 | Cite as

Selenium–Chromium(VI) Interaction Regulates the Contents and Correlations of Trace Elements in Chicken Brain and Serum

  • Yiran Zhu
  • Peng Chen
  • Huiyu Wan
  • Yang Wang
  • Pan Hao
  • Yongxia LiuEmail author
  • Jianzhu LiuEmail author
Article

Abstract

This study aims to investigate the contents of trace elements in the brain and serum of male chickens and the effect of selenium–chromium(VI) interaction. A chronic experimental model was established by supplementing 22.14 mg/kg K2Cr2O7 with 0.00, 0.31, 0.63, 1.25, 2.50, and 5.00 mg/kg Na2SeO3 mg/kg B.W. to water for chicken daily. After 14, 28, and 42 days of exposure to the solution, the brain and serum of chickens from each group were collected to detect the levels of Ca, Cu, Mn, Fe, Zn, and Mg by inductively coupled plasma mass spectrometer (ICP-MS). Cr(VI) time-dependently accumulated in the brain and serum. The contents of Cr increased both in the brain and serum with prolonged exposure. Cr contents in the brain and serum decreased in all Se groups compared with those in only Cr-treated groups. Ca contents decreased with prolonged exposure and increasing Se dosage. The contents of Cu and Mn increased on the 28th day but decreased on the 42nd day in the brain and serum. Fe and Zn contents decreased in the serum under prolonged exposure and increased on the 28th day but decreased on the 42nd day in the brain. Cr exposure did not significantly affect Mg contents in the brain but slightly decreased those in the serum. Therefore, appropriate doses of Se affected Cr accumulation, leading to adjustments in the contents and correlations of trace elements.

Keywords

Chromium Selenium Male chickens Trace elements Brain 

Notes

Acknowledgements

This work was supported by the National Key R&D Program (2016YFD0501208, 2016YFD0501007) and the Shandong Modern Agricultural Technology & Industry System (No. SDAIT-11-04).

Compliance with Ethical Standards

The animal care and use procedures applied in the study were conducted under the protocols approved by the Institutional Animal Care and Use Committee of Shandong Agricultural University (SDAU 2015-07).

Conflict of Interest

The authors declare that they have no competing interests.

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.College of Veterinary Medicine, Research Center for Animal Disease Control Engineering, Shandong ProvinceShandong Agricultural UniversityTai’anChina
  2. 2.Research Center for Animal Disease Control EngineeringShandong Agricultural UniversityTai’anChina

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