Biological Trace Element Research

, Volume 172, Issue 2, pp 521–527 | Cite as

Antioxidant Potential and In Situ Analysis of Major and Trace Element Determination of Ood-saleeb, a Known Unani Herbal Medicine by ICP-MS

  • Mohammad Raish
  • Ajaz Ahmad
  • Khalid M. Alkharfy
  • Fahad I. Al-Jenoobi
  • Abdullah M. Al-Mohizea
  • Kazi Mohsin
  • Syed Rizwan Ahamad
  • Naushad Ali
  • Faiyaz Shakeel
Article
First Online:
Received:
Accepted:

Abstract

The intention of the present research work was to investigate the antioxidant activity and trace element analysis of Ood-saleeb, a known herbal medicine. Preliminary screening of phytochemicals showed that the extract of Ood-saleeb had flavonoids and phenolics. The significant activities in all antioxidant assays were observed in the extract of Ood-saleeb in comparison with the standard antioxidant with respect to dose of Ood-saleeb. Incredible activities to scavenge reactive oxygen species were also observed by the extract of Ood-saleeb. The IC50 values of all factors were determined using ascorbic acid as a standard. The inductive coupled plasma-mass spectroscopy (ICP-MS) was employed for the estimation of trace elements in Ood-saleeb extract. The concentrations of up to 18 elements were detected successfully. Silicon was found in high concentration (85.3 μg/g) while lithium was in low concentration (3 ng/g). The trace elements in the sample were found at different percentage levels which play a key role in the treatment of diseases.

Keywords

Antioxidant Ascorbic acid Ood-saleeb Trace elements ICP-MS 
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Notes

Acknowledgments

The author would like to extend their sincere appreciation to the Deanship of Scientific Research at King Saud University for its funding through research group number (RG# 1435-017).

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no competing interests.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Mohammad Raish
    • 1
  • Ajaz Ahmad
    • 2
  • Khalid M. Alkharfy
    • 2
  • Fahad I. Al-Jenoobi
    • 1
  • Abdullah M. Al-Mohizea
    • 1
  • Kazi Mohsin
    • 1
  • Syed Rizwan Ahamad
    • 3
  • Naushad Ali
    • 4
  • Faiyaz Shakeel
    • 1
    • 5
  1. 1.Department of Pharmaceutics, College of PharmacyKing Saud UniversityRiyadhSaudi Arabia
  2. 2.Department of Clinical Pharmacy, College of PharmacyKing Saud UniversityRiyadhSaudi Arabia
  3. 3.Research Centre, College of PharmacyKing Saud UniversityRiyadhSaudi Arabia
  4. 4.Quality Assurance Unit, College of PharmacyKing Saud UniversityRiyadhSaudi Arabia
  5. 5.Center of Excellence in Biotechnology Research (CEBR)King Saud UniversityRiyadhSaudi Arabia

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