Biological Trace Element Research

, Volume 142, Issue 2, pp 127–129 | Cite as

Reversible Hypomagnesaemia-Induced Subacute Cerebellar Syndrome

  • Saam SedehizadehEmail author
  • Michael Keogh
  • Adrian J. Wills


Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbeat nystagmus, cerebellar ataxia, generalised convulsions and a supraventricular tachycardia. On MRI imaging, a transient lesion of the cerebellar nodulus was observed, which has not, to our knowledge, been previously described in isolated hypomagnesaemia.


Cerebellar ataxia Metabolic disease Hypomagnesaemia 


Competing interest

None declared.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Saam Sedehizadeh
    • 1
    Email author
  • Michael Keogh
    • 2
  • Adrian J. Wills
    • 1
  1. 1.Department of Neurology, Queens Medical CentreNottingham University Hospitals NHS TrustNottinghamUK
  2. 2.Department of NeurologyNewcastle Upon Tyne Hospitals NHS TrustNewcastle Upon TyneUK

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