Biological Trace Element Research

, Volume 128, Issue 2, pp 184–190 | Cite as

Differential Effects of Sodium Selenite and Nano-Se on Growth Performance, Tissue Se Distribution, and Glutathione Peroxidase Activity of Avian Broiler



The present research evaluated differential effects of sodium selenite and nano-Se on growth performance, tissue Se distribution, and glutathione peroxidase (GSH-Px) activity of avian broiler. Broilers were randomly segregated into 12 groups so that three replicates were available for each of the three treatments (T-1, T-2, and T-3) and control groups. The control groups were fed basal diets without Se addition. T-1, T-2, and T-3 were fed with diets containing 0.2 mg kg−1 sodium selenite, 0.2 mg kg−1 nano-Se, and 0.5 mg kg−1 nano-Se, respectively. Compared with the control, Se supplementation remarkably improved daily weight gain and survival rate and decreased feed conversion ratio (P < 0.05). However, no significant difference was observed between T-1, T-2, and T-3. The tissue Se content was significantly higher (P < 0.05) in Se-supplemented groups than the control, and T-3 showed the highest. Furthermore, higher Se content was observed in liver, and there was a significant difference (P < 0.05) compared with that in muscle. As for serum and hepatic GSH-Px activities, Se supplementation remarkably improved GSH-Px activity (P < 0.05), and there was no significant difference (P > 0.05) between treatments (T-1, T-2, and T-3).


Selenium Sodium selenite Nano-Se Growth performance Glutathione peroxidase Avian broiler 



This study was supported by the Doctoral Natural Science Foundation of University (No. 1110XJ-030628). We also acknowledge valuable help provided by all involved workers.


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Copyright information

© Humana Press Inc. 2008

Authors and Affiliations

  1. 1.Key Laboratory of Food Safety of Zhejiang Province, Food Quality & Safety DepartmentZhejiang Gongshang UniversityHangzhouChina
  2. 2.HangzhouChina

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