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Adrenocorticotropic Hormone and Cortisol Levels in Athletes and Sedentary Subjects at Rest and Exhaustion: Effects of Magnesium Supplementation

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Abstract

The effects of a 1-month exercise program and magnesium supplementation on the adrenocorticotropic hormone and cortisol levels were studied in young tae-kwon-do and sedentary subjects both at rest and exhaustion. The hormone levels were compared before and after supplementation with 10 mg of magnesium (as magnesium sulfate) per kilogram of body weight. Both exercise and magnesium supplements caused significant increases of the adrenocorticotropic hormone (p < 0.05). The cortisol levels were increased in training subjects receiving supplements (p < 0.05) but not so in subjects that either trained or received magnesium supplements in an independent manner. The cortisol levels measured in resting individuals were higher in the supplemented and non-supplemented athletes than those in sedentary subjects (p < 0.05). The results of this study show that exercise and/or magnesium supplementation causes a rise of the adrenocorticotropic hormone, whereas cortisol is increased only as a result of combined exhaustion and magnesium supplements.

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References

  1. 1.

    Mastorakos G, Pavlatou M (2005) Exercise as a stress model and the interplay between the hypothalamus–pituitary–adrenal and the hypothalamus–pituitary–thyroid axes. Horm Metab Res 37:577–584

  2. 2.

    McMurray RG, Hackney AC (2005) Interactions of metabolic hormones, adipose tissue and exercise. Sports Med 35:393–412

  3. 3.

    Hackney AC, McMurray RG, Judelson DA, Harrell JS (2003) Relationship between caloric intake, body composition, and physical activity to leptin, thyroid hormones, and cortisol in adolescents. Jpn J Physiol 53:475–479

  4. 4.

    Huang WS, Yu MD, Lee MS, Cheng CY, Yang SP, Chin HM, Wu SY (2004) Effect of treadmill exercise on circulating thyroid hormone measurements. Med Princ Pract 13:15–19

  5. 5.

    Duma E, Orbai P, Derevenco P (1998) Blood levels of some electrolytes and hormones during exercise in athletes. Rom J Physiol 35:55–60

  6. 6.

    Castellani JW, Young AJ, Stulz DA, DeGroot DW, Blanchard LA, Staab JE, Sawka MN (2002) Pituitary-adrenal and pituitary-thyroid hormone responses during exercise-cold exposure after 7 days of exhaustive exercise. Aviat Space Environ Med 73:544–550

  7. 7.

    Viru M, Jansson E, Viru A, Sundberg CJ (1998) Effect of restricted blood flow on exercise-induced hormone changes in healthy men. Eur J Appl Physiol Occup Physiol 77:517–522

  8. 8.

    Bosco C, Tihanyl J, Rivalta L, Parlato G, Tranquilli C, Pulvirenti G, Foti C, Viru M, Viru A (1996) Hormonal responses in strenuous jumping effort. Jpn J Physiol 46:93–98

  9. 9.

    McMurray RG, Eubank TK, Hackney AC (1995) Nocturnal hormonal responses to resistance exercise. Eur J Appl Physiol Occup Physiol 72:121–126

  10. 10.

    Deligiannis A, Karamouzis M, Kouidi E, Mougios V, Kallaras C (1993) Plasma TSH, T3, T4 and cortisol responses to swimming at varying water temperatures. Br J Sports Med 27:247–250

  11. 11.

    Limanova Z, Sonka J, Kratochvil O, Sonka K, Kanka J, Sprynarova S (1983) Effects of exercise on serum cortisol and thyroid hormones. Exp Clin Endocrinol 81:308–314

  12. 12.

    Urhausen A, Gabriel HH, Kindermann W (1998) Impaired pituitary hormonal response to exhaustive exercise in overtrained endurance athletes. Med Sci Sports Exerc 30:407–414

  13. 13.

    Rietjens GJ, Kuipers H, Adam JJ, Saris WH, van Breda E, van Hamont D, Keizer HA (2005) Physiological, biochemical and psychological markers of strenuous training-induced fatigue. Int J Sports Med 26:16–26

  14. 14.

    Kokalas N, Tsalis G, Tsigilis N, Mougios V (2004) Hormonal responses to three training protocols in rowing. Eur J Appl Physiol 92:128–132

  15. 15.

    van der Pompe G, Bernards N, Kavelaars A, Heijnen C (2001) An exploratory study into the effect of exhausting bicycle exercise on endocrine and immune responses in post-menopausal women: relationships between vigour and plasma cortisol concentrations and lymphocyte proliferation following exercise. Int J Sports Med 22:447–453

  16. 16.

    Lukaski HC, Bolonchuk WW, Kelvay L, Milne DB, Sandstead HH (1983) Maximal oxygen consumption as related to magnesium, copper and zinc nutriture. Am J Clin Nutr 37:407–415

  17. 17.

    Lukaski HC, Nielsen FH (2002) Dietary magnesium depletion affects metabolic responses during sub maximal exercise in postmenopausal women. J Nutr 132:930–935

  18. 18.

    Bohl CH, Volpe SL (2002) Magnesium and exercise. Crit Rev Food Sci Nutr 42:533–563

  19. 19.

    Golf SW, Bender S, Gruttner J (1998) On the significance of magnesium in extreme physical stress. Cardiovasc Drugs Ther 12:197–202

  20. 20.

    Keen CL, Lowney P, Gershwin ME, Hurley LS, Stem JS (1987) Dietary Magnesium Intake Influences Exercise Capacity and Hematological Parameters in Rats. Metabolism 36:788–793

  21. 21.

    Held K, Antonijevic IA, Kunzel H, Uhr M, Wetter TC, Golly IC, Steiger A, Murck H (2002) Oral Mg (2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry 35:135–143

  22. 22.

    Murck H, Steiger A (1998) Mg2+reduces ACTH secretion and enhances spindle power without changing delta power during sleep in men–possible therapeutic implications. Psychopharmacology (Berl) 137:247–252

  23. 23.

    Apple JK, Kegley EB, Maxwell CV, Rakes LK, Galloway D, Wistuba TJ (2005) Effects of dietary magnesium and short-duration transportation on stress response, postmortem muscle metabolism, and meat quality of finishing swine. J Anim Sci 83:1633–1645

  24. 24.

    Zorba E (2001) Fiziksel Uygunluk. Gazi Kitapevi, Ankara, p 245

  25. 25.

    Clarkson PM (1991) Minerals: exercise performance and supplementation in athletes. J Sports Sci 9:91–116

  26. 26.

    Raastad T, Bjoro T, Hallen J (2000) Hormonal responses to high- and moderate-intensity strength exercise. Eur J Appl Physiol 82:121–128

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Correspondence to Vedat Cinar.

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Cinar, V., Mogulkoc, R., Baltaci, A.K. et al. Adrenocorticotropic Hormone and Cortisol Levels in Athletes and Sedentary Subjects at Rest and Exhaustion: Effects of Magnesium Supplementation. Biol Trace Elem Res 121, 215–220 (2008). https://doi.org/10.1007/s12011-007-8052-0

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Keywords

  • Tae-kwon-do
  • Magnesium supplementation
  • Rest
  • Exhaustion
  • ACTH
  • Cortisol