Applied Biochemistry and Biotechnology

, Volume 169, Issue 4, pp 1134–1146 | Cite as

Antiviral and Antibacterial Polyurethanes of Various Modalities

Article

Abstract

We have prepared and characterized a new polyurethane-based antimicrobial material, N,N-dodecyl,methyl-polyurethane (Quat-12-PU). It exhibits strong antiviral and antibacterial activities when coated (as an organic solution or an aqueous nanosuspension) onto surfaces and antibacterial activity when electrospun into nanofibers. Quat-12-PU surfaces are able to kill airborne Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli bacteria, as well as inactivate the enveloped influenza virus (but not the non-enveloped poliovirus).

Keywords

Antiviral Antibacterial Polyurethane Nanoparticles Nanofibers 

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of BioengineeringUniversity of Colorado Denver Anschutz Medical CampusAuroraUSA
  2. 2.Department of ChemistryMassachusetts Institute of TechnologyCambridgeUSA
  3. 3.Department of Biological EngineeringMassachusetts Institute of TechnologyCambridgeUSA
  4. 4.Department of Bioengineering and McGowan Institute for Regenerative MedicineUniversity of PittsburghPittsburghUSA

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