Annals of Ophthalmology

, Volume 39, Issue 2, pp 152–157

Conjunctival Pigmentation in Stevens-Johnson Syndrome

  • Graciana Fuentes-Páez
  • Maria C. Mendez
  • Javier Montañez
  • Jose M. Herreras
  • Maria A. Saornil
  • Margarita Calonge
Case Report

DOI: 10.1007/s12009-007-0010-0

Cite this article as:
Fuentes-Páez, G., Mendez, M.C., Montañez, J. et al. Ann Ophthalmol (2007) 39: 152. doi:10.1007/s12009-007-0010-0

Editor’s Preface

Examination of the conjunctiva/sclera and surrounding structures is an important component of any physical exam. The articles by Dr. Fuentes-Paez et al. and by Dr. Sharma et al. provide critical information for a good exam of the eye and surrounding structures. Reading these two articles in conjunction with a basic text of ocular microanatomy will provide a great refresher course on this topic. More importantly, it will also provide an invaluable guide to understanding the dynamics of changes in color and texture of the conjunctiva and surrounding tissue.

Abstract

We report a 29-year-old white woman with conjunctival pigmentation after a Stevens-Johnson syndrome (SJS) episode triggered by sulfasalazine. The patient developed bilateral tarsal and forniceal conjunctiva and black pigmentation. Diagnostic biopsy showed stromal monocyte infiltration consistent with chronic phase SJS and conjunctival pigment of melanic origin that was not due to drug deposition. Treatment with topical steroids and unpreserved artificial tears resulted in improvement of clinical symptoms; however, pigmentation was unchanged after 2 years.

Copyright information

© American Society of Contempary Ophthalmology & The Intenational Association of Ocular Surgeons 2007

Authors and Affiliations

  • Graciana Fuentes-Páez
    • 1
  • Maria C. Mendez
    • 2
  • Javier Montañez
    • 3
  • Jose M. Herreras
    • 1
  • Maria A. Saornil
    • 2
  • Margarita Calonge
    • 1
  1. 1.Ocular Immunology Unit, IOBA, Facultad de MedicinaUniversity of ValladolidValladolidSpain
  2. 2.Miguel N. Burnier Registry of Pathology, Institute of Ophthalmobiology (IOBA)University of ValladolidValladolidSpain
  3. 3.Hospital Son DuretaPalma de MallorcaSpain

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