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Annals of Ophthalmology

, Volume 32, Issue 3, pp 245–248 | Cite as

Ocular complications in inflammatory bowel disease

  • Yildiz Ozdemir
  • C. Banu Cosar
  • Feyza Önder
  • Gülcan Kural
  • Ülkü Dagli
Original Article
  • 14 Downloads

Abstract

We performed ophthalmologic evaluation in 93 patients with inflammatory bowel disease (78 with ulcerative colitis and 15 with Crohn's disease). Ocular complications developed in 12 patients (age, 16 to 53 years): 10 with ulcerative colitis and 2 with Crohn's disease. Ocular complications included episcleritis (n=2), subepithelial infiltrates (n=2), uveitis (n=2), perivascular sheathing (n=3), retinal vasculitis (n=1), and multifocal infiltrates (n=5).

Keywords

Inflammatory Bowel Disease Ulcerative Colitis Uveitis Branch Retinal Vein Occlusion Ocular Complication 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Danzi ST. Extraintestinal manifestations of idiopathic inflammatory bowel disease. Arch Intern Med. 1988;148:297.PubMedCrossRefGoogle Scholar
  2. 2.
    Rankin GB, Watts HD, Melnick CS, et al. National Cooperative Crohns' Disease Study. Extraintestinal manifestations and perianal complications. Gastroenterology. 1979;77:914–920.PubMedGoogle Scholar
  3. 3.
    Greenstein AJ, Janowitz HD. Sachar DB. The extraintestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients. Medicine. 1976;55:401–412.PubMedGoogle Scholar
  4. 4.
    Petrelli EA, McKinley M, Troncale FJ. Ocular manifestations of inflammatory bowel disease. Ann Ophthalmol. 1982;14:356–360.PubMedGoogle Scholar
  5. 5.
    Bilson FA, De Dombal FT, Watkins G, et al. Ocular complications of ulcerative colitis. Gut. 1967;8:102–106.Google Scholar
  6. 6.
    Blase WP, Knox DL, Green WR., Granulomatous conjunctivitis in a patient, with Crohn's disease. Br J Ophthalmol. 1984;68:901–903.PubMedGoogle Scholar
  7. 7.
    Schulman MF, Sugar A. Peripheral corneal infiltrates in inflammatory bowel disease. Ann Ophthalmol. 1981;13:109–111.PubMedGoogle Scholar
  8. 8.
    Korelitz BI, Coles RS. Uveitis (iritis) associated with ulcerative and granulomatous colitis. Gastroenterology. 1967;52:78–82.PubMedGoogle Scholar
  9. 9.
    Hofley P, Roarty J, McGinnity G, Griffiths M, et al. Asymptomatic uveitis in children with chronic inflammatory bowel diseases J Pediatr Gastroenterol Nutr. 1993;17:397–400.PubMedCrossRefGoogle Scholar
  10. 10.
    Baiocco PJ, Gorman BD, Korelitz BI., Uvetis occuring after colectomy and ileal-rectal sleeve anastomosis for ulcerative colitis. Dig Dis Sci. 1984;29:570–572.PubMedCrossRefGoogle Scholar
  11. 11.
    Bonvin RR, Dosso AA, Safran AB. Occlusion of the ophthalmic artery in Crohn's disease. Klin Monatsbl Augenheilkd. 1994;5:450–452.Google Scholar
  12. 12.
    Weinstein JM, Koch K, Lane S. Orbital pseudotumor in Crohn's colitis. Ann Ophthalmol. 1984;16:275–278.PubMedGoogle Scholar
  13. 13.
    Macoul KL. Ocular changes in granulomatous ileocolitis. Arch Ophthalmol. 1970;84:95–97.PubMedGoogle Scholar
  14. 14.
    Heuer DK, Gager WE, Reeser FH. Ischemic optic neuropathy associated with Crohn's disease. J Clin Neuro Ophthalmol. 1982;2:175–181.Google Scholar
  15. 15.
    Hofley P, Roarty J, Mc Ginnity G, et al. Asymptomatic uveitis in children with chronic inflammatory bowel diseases. J Pediatr Gastroenterol Nutr. 1993;17:397–400.PubMedCrossRefGoogle Scholar
  16. 16.
    Sedwick LA, Kingele TG, Burde RM, et al. Optic neuritis in inflammatory bowel disease. J Clin Neuro Ophthalmol. 1984;4:3–6.Google Scholar
  17. 17.
    Wirostko E, Johnson L, Wirostko B. Ulcerative colitis associated chronic uveitis. J Submicrosc Cytol Pathol. 1990;22:231–239.PubMedGoogle Scholar
  18. 18.
    Knox DL, Schactat AP, Mustanen E. Primary, secondary and coincidental ocular complications of Crohn's disease. Ophthalmology. 1984;91:163–173.PubMedGoogle Scholar
  19. 19.
    Bonuman MF, Sugar A. Peripheral corneal infiltrates in inflammatory bowel disease. Ann Ophthalmol. 1981;13:109–111.Google Scholar
  20. 20.
    Salmon JF, Wright JP, Murray AD. Ocular inflammation in Crohn's disease. Br J Ophthalmol. 1991;98:480–484.Google Scholar
  21. 21.
    Hopkins DJ, Horan E, Burton IL, et al. Ocular disorders in a series of 332 patients with Crohn's disease. Br J Ophthalmol. 1974;58:732–737.PubMedGoogle Scholar
  22. 22.
    Sarkis H, Soukasian MD, Foster S, et al. Treatment strategies for scleritis and uveitis associated with inflammatory bowel disease. Am J Ophthalmol. 1994;118:601–611.Google Scholar
  23. 23.
    Brynoskov J, Freund L, Rasmussen SN, et al. A placebo-controlled double-blind randomized trial of cyclosporine therapy in active chronic Crohn's disease. N Engl J Med 1989;321:845.CrossRefGoogle Scholar
  24. 24.
    Lichtiger S, Present DH. Preliminary report: cyclosporine in treatment of severe active ulcerative colitis. Lancet 1990;336:16.PubMedCrossRefGoogle Scholar
  25. 25.
    Salmon JF, Wright JP, Bowen R, et al. Granulomatous uveitis in Crohn's disease. Arch Ophthalmol 1989;107:718–719.PubMedGoogle Scholar
  26. 26.
    Schuettenberg SP. Nodular scleritis, episcleritis and anterior uveitis as ocular complications of Crohn's disease. J Am Ophthalmol Assoc. 1991;62:377–381.Google Scholar
  27. 27.
    Boskowitch SA, Lowder CY, Meisler DM, et al. Systemic diseases associated with intermediate uveitis. Cleve Clin J Med. 1993;60:460–465.Google Scholar
  28. 28.
    Duker JS, Brown GC, Brooks L. Retinal vasculitis in Crohn's disease. Am J Ophthalmol. 1987;103:664–668.PubMedGoogle Scholar
  29. 29.
    Ernst BB, Lowder CY, Meisler D, et al. Posterior segment manifestations of inflammatory bowel disease. Ophthalmology. 1991; 98:1272–1280.PubMedGoogle Scholar
  30. 30.
    Ruby AJ, Jampol LM. Crohn's disease and retinal vascular disease. Am J Ophthalmol. 1990;110:349–353.PubMedGoogle Scholar
  31. 31.
    Kelly IM, Frith PA, Hyman NM, et al. Retinal periphlebitis in ulcerative colitis. Postgrad Med. 1990;66:565–567.CrossRefGoogle Scholar
  32. 32.
    Tripathi R, Kirschner B, Kipp M. Corticosteroid treatment for inflammatory bowel disease in pediatric patients increases intraocular pressure. Gastroenterology. 1992;102:1957–1961.PubMedGoogle Scholar
  33. 33.
    Tripathi RC, Kipp MA, Tripathi BJ, et al. Ocular toxicity of prednisone in pediatric patients with inflammatory bowel disease. Lens Eye Toxic Res. 1992;9:469–482.PubMedGoogle Scholar

Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Yildiz Ozdemir
    • 1
  • C. Banu Cosar
    • 1
  • Feyza Önder
    • 1
  • Gülcan Kural
    • 1
  • Ülkü Dagli
    • 2
  1. 1.Eye Clinic IAnkara Numune HospitalAnkaraTurkey
  2. 2.Gastroenterology ClinicAnkara Yüksek Ihtisas HospitalAnkaraTurkey

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