Advertisement

Annals of Ophthalmology

, Volume 32, Issue 3, pp 219–224 | Cite as

Ocular manifestations in chronic fatigue syndrome

  • Leonardo Mastropasqua
  • Marco Ciancaglini
  • Paolo Carpineto
  • Antonella Iezzi
  • Delia Racciatti
  • Gennaro Falconio
  • Eduardo Zuppardi
  • Eligio Pizzigallo
Original Article

Abstract

A case-control masked study was performed in 37 patients with chronic fatigue syndrome (GFS) to evaluate ocular signs, symptoms, and functional parameters. A significant association was found between CFS and blurred vision at near, foggy vision, shadowed vision, headaches, and photophobia. Blurred vision, foggy vision, and headaches were associated with abnormal oculomotor function, and shadowed vision and photophobia were associated with tear deficiency. These data suggest that CFS affects the ocular system.

Keywords

Chronic Fatigue Syndrome Pupil Diameter Ocular Symptom Chronic Fatigue Syndrome Patient Ocular Manifestation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Holmes GP, Kaplan JE, Gantz NM. Chronic fatigue syndrome: a working case definition. Ann Intern Med. 1988;108:387–389.PubMedGoogle Scholar
  2. 2.
    Fukuda K, Straus SE, Hickie I, and the International Chronic Fatigue Syndrome Study Group: The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994;121:953–959.PubMedGoogle Scholar
  3. 3.
    Kroenke K, Wood DR, Mangelsdorff AD. Chronic fatigue in primary care: prevalence, patient characteristics, and outcome. JAMA. 1988;260:929–934.PubMedCrossRefGoogle Scholar
  4. 4.
    Behan PO, Behan WMH, Bell EJ. The postviral fatigue syndrome: an analysis of the findings in 50 cases. J Infect Dis. 1985;10:211–222.Google Scholar
  5. 5.
    Swartz MN. The chronic fatigue syndrome—one entity or many? N Engl J Med. 1988;319:1726–1728.PubMedCrossRefGoogle Scholar
  6. 6.
    Gantz NM, Holmes GP. Treatment of patients with chronic fatigue syndrome. Drugs. 1989;38:855–862.PubMedGoogle Scholar
  7. 7.
    Komaroff AL, Goldberg D. The chronic fatigue syndrome: definition, current status, and lessons for fibromyalgia research. J Rheumatol. 1989;19:23–27.Google Scholar
  8. 8.
    Straus SE, Dale JK, Wright R. Allergy and the chronic fatigue syndrome. J Allergy Clin Immunol. 1988;81:791–795.PubMedCrossRefGoogle Scholar
  9. 9.
    Caffery BE. The ocular signs and symptoms of chronic fatigue syndrome. In: Proceedings of the American Academy of Optometry Annual Meeting; December 1990; Nashville, Tenn; 21–24.Google Scholar
  10. 10.
    Caffery BE, Josephson JE, Samek MJ. The ocular signs and symptoms of chronic fatigue syndrome. J Am Optom Assoc. 1994;65:187–191.PubMedGoogle Scholar
  11. 11.
    Karnezis TA, Murphy MB, Weber RR. Effects of selective dopamine-1-receptor activation on intraocular pressure in man. Exp Eye Res. 1988;47:689–698.PubMedCrossRefGoogle Scholar
  12. 12.
    Wong R, Lopaschuk G, Zhu G. Skeletal muscle metabolism in the chronic fatigue syndrome. Chest. 1992;101:1716–1722.Google Scholar
  13. 13.
    Behan WNM, More IAR, Behan PO. Mitochondrial abnormalities in the postviral fatigue syndrome. Acta Neuropathol. 1991;83:61–65.PubMedCrossRefGoogle Scholar
  14. 14.
    Pizzigallo E, Di Girolamo A, Montanari G. Alterations in muscles of CFS patients at morphological, biochemical, and molecular levels. In: Proceedings of the First World Congress on Chronic Fatigue Syndrome and Related Disorders; Brussels, Belgium; November 9–11, 1995; 17.Google Scholar
  15. 15.
    Holmes GP, Kaplan JE, Steward SA. A cluster of patients with a chronic mononucleosis-like syndrome: is Epstein-Barr virus the cause? JAMA. 1987;257:2297–2302.PubMedCrossRefGoogle Scholar
  16. 16.
    Strauss SE, Dale JK, Peter JB. Circulating lymphokines in the chronic fatigue syndrome. J Infect Dis. 1989;160:1085–1086.Google Scholar
  17. 17.
    Caligiuri M, Murray C, Buchwald D. Phenotypic and functional deficiency of natural killer cells in patients with chronic fatigue syndrome. J Immunol. 1987;138:3306–3313.Google Scholar
  18. 18.
    Potaznick W, Kozol N. Ocular manifestation of chronic fatigue syndrome and immune dysfunction syndrome. Opt Vis Sci. 1992;69:811–814.CrossRefGoogle Scholar

Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Leonardo Mastropasqua
    • 1
  • Marco Ciancaglini
    • 1
  • Paolo Carpineto
    • 1
  • Antonella Iezzi
    • 2
  • Delia Racciatti
    • 2
  • Gennaro Falconio
    • 1
  • Eduardo Zuppardi
    • 1
  • Eligio Pizzigallo
    • 2
  1. 1.Institute of OphthalmologyUniversity of ChietiChietiItaly
  2. 2.Clinic of Infectious DiseasesUniversity of ChietiChietiItaly

Personalised recommendations