Is There a Preferred Articulating Spacer Technique for Infected Knee Arthroplasty?: A Preliminary Study
- 428 Downloads
- 21 Citations
Abstract
Background
Periprosthetic infection in TKA is a devastating and challenging problem for both patients and surgeons. Two-stage exchange arthroplasty with an interval antibiotic spacer reportedly has the highest infection control rate. Studies comparing static spacers with articulating spacers have reported varying ROM after reimplant, which could be due to differences in articulating spacer technique.
Questions/purposes
We therefore determined whether one of three articulating spacer techniques was superior in terms of (1) infection control, (2) final ROM, and (3) cost.
Patients and Methods
We retrospectively reviewed 53 patients with infected TKAs who had two-stage exchange arthroplasty with one of three techniques with articulating spacers: autoclaving an original component (n = 15), a new femoral component (n = 16), and a silicone mold component (n = 22). We compared infection control, ROM, and cost. Minimum followup was 12 months (mean, 39 months; range, 12–105 months).
Results
We found no difference in infection control among the three techniques. Infection control was achieved in 13 of 15 (86.7%) autoclaved original component spacers at mean 73 months (range, 37–105 months), 15 of 16 (93.8%) new femoral component spacers at mean 19 months (range, 12–32 months), and 20 of 22 (90.9%) silicone mold component spacers at mean 32 months (range, 14–56 months). Mean final flexion was 95.7°, 98.3°, and 93.8°, respectively. Direct costs for all implants, molds, cement, and antibiotics were $932, $3589, and $3945, respectively.
Conclusions
We found comparable infection control and ROM for the three techniques. Direct cost was least for the autoclaved original component technique.
Level of Evidence
Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
Keywords
Infection Control Space Technique Polyethylene Insert Silicone Mold Reinfection RateNotes
Acknowledgments
The authors thank Paul Lender (University of Minnesota) and Penny Tatman, MPH (HealthEast Care System, St Paul, MN) for their help with the statistical analysis.
References
- 1.Azzam K, McHale K, Austin M, Purtill JJ, Parvizi J. Outcome of a second two-stage reimplantation for periprosthetic knee infection. Clin Orthop Relat Res. 2009;467:1706–1714.PubMedCrossRefGoogle Scholar
- 2.Bengston S, Knutson K, Lidgren L. Treatment of infected knee arthroplasty. Clin Orthop Relat Res. 1989;245:173–178.PubMedGoogle Scholar
- 3.Blom AW, Brown J, Taylor AH, Pattison G, Whitehouse S, Bannister GC. Infection after total knee arthroplasty. J Bone Joint Surg Br. 2004;86:688–691.PubMedCrossRefGoogle Scholar
- 4.Booth RE, Lotke PA. The results of spacer block technique in revision of infected total knee arthroplasty. Clin Orthop Relat Res. 1989;248:57–60.PubMedGoogle Scholar
- 5.Calton TF, Fehring TK, Griffin WL. Bone loss associated with the use of spacer blocks in infected total knee arthroplasty. Clin Orthop Relat Res. 1997;345:148–154.PubMedCrossRefGoogle Scholar
- 6.Chevrel G, Schott AM, Fontanges E, Charrin JE, Lina-Granade G, Duboeuf F, Garnero P, Arlot M, Raynal C, Meunier PJ. Effects of oral alendronate on BMD in adult patients with osteogenesis imperfecta: a 3-year randomized placebo-controlled trial. J Bone Miner Res. 2006;21:300–306.PubMedCrossRefGoogle Scholar
- 7.Cohen JC, Hozack WJ, Cuckler JM, Booth RE. Two-stage reimplantation of septic total knee arthroplasty: report of three cases using an antibiotic-PMMA spacer block. J. Arthroplasty. 1988;3:369–377.PubMedCrossRefGoogle Scholar
- 8.Cuckler J. The infected total knee: management options. J Arthroplasty. 2005;20:33–36.PubMedCrossRefGoogle Scholar
- 9.Durbhakula S, Czajka J, Fuchs M, Uhl R. Antibiotic-loaded articulating cement spacer in the 2-stage exchange of infected total knee arthroplasty. J Arthroplasty. 2004;19:768–774.PubMedCrossRefGoogle Scholar
- 10.Emerson R, Muncie M, Tarbox T, Higgins L. Comparison of a static with a mobile spacer in total knee infection. Clin Orthop Relat Res. 2002;404:132–138.PubMedCrossRefGoogle Scholar
- 11.Fehring TK, Odum S, Calton TF, Mason JB. Articulating versus static spacers in revision total knee arthroplasty for sepsis. The Ranawat Award. Clin Orthop Relat Res. 2000;380:9–16.CrossRefGoogle Scholar
- 12.Freeman M, Fehring T, Odum S, Fehring K, Griffin W, Mason JB. Functional advantage of articulating versus static spacers in 2-stage revision for total knee arthroplasty infection. J Arthroplasty. 2007;22:1116–1121.PubMedCrossRefGoogle Scholar
- 13.Hall W, Ramachandran R, Narayan S, Jani A, Vijayakumar S. An electronic application for rapidly calculating Charlson comorbidity score. BMC Cancer. 2004;4:94–94.PubMedCrossRefGoogle Scholar
- 14.Hebert CK, Williams RE, Levy RS, Barrack RL. Cost of treating an infected total knee replacement. Clin Orthop Relat Res. 1996;331:140–145.PubMedCrossRefGoogle Scholar
- 15.Hofmann A, Goldberg T, Tanner A, Kurtin S. Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience. Clin Orthop Relat Res. 2005;430:125–131.PubMedCrossRefGoogle Scholar
- 16.Hofmann AA, Kane KR, Tkach TK, Plaster RL, Camargo MP. Treatment of infected total knee arthroplasty using an articulating spacer. Clin Orthop Relat Res. 1995;321:45–54.PubMedGoogle Scholar
- 17.Huang HT, Su JY, Chen SK. The results of articulating spacer technique for infected total knee arthroplasty. J Arthroplasty. 2006;21:1163–1168.PubMedCrossRefGoogle Scholar
- 18.Insall JN, Thompson FM, Brause BD. Two-stage reimplantation for the salvage of infected total knee arthroplasty. J Bone Joint Surg Am. 1983;65:1087–1098.PubMedGoogle Scholar
- 19.Jacobs C, Christensen C, Berend M. Static and mobile antibiotic-impregnated cement spacers for the management of prosthetic joint infection. J Am Acad Orthop Surg. 2009;17:356–368.PubMedGoogle Scholar
- 20.Jämsen E, Sheng P, Halonen P, Lehto MU, Moilanen T, Pajamäki J, Puolakka T, Konttinen YT. Spacer prostheses in two-stage revision of infected knee arthroplasty. Int Orthop. 2006;30:257–261.PubMedCrossRefGoogle Scholar
- 21.Jämsen E, Stogiannidis I, Malmivaara A, Pajamäki J, Puolakka T, Konttinen Y. Outcome of prosthesis exchange for infected knee arthroplasty: the effect of treatment approach. Acta Orthop. 2009;80:67–77.PubMedCrossRefGoogle Scholar
- 22.Leone J, Hanssen A. Management of infection at the site of a total knee arthroplasty. Instr Course Lect. 2006;55:449–461.PubMedGoogle Scholar
- 23.Lombardi A, Karnes J, Berend K. A motion maintaining antibiotic delivery system. J Arthroplasty. 2007;22:50–55.PubMedCrossRefGoogle Scholar
- 24.McPherson EJ, Lewonowski K, Dorr LD. Techniques in arthroplasty: use of an articulated PMMA spacer in the infected total knee arthroplasty. J Arthroplasty. 1995;10:87–89.PubMedCrossRefGoogle Scholar
- 25.National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control. 2004;32:470–485.CrossRefGoogle Scholar
- 26.Pietsch M, Hofmann S, Wenisch C. Treatment of deep infection of total knee arthroplasty using a two-stage procedure. Oper Orthop Traumatol. 2006;18:66–87.PubMedCrossRefGoogle Scholar
- 27.Pitto RP, Castelli CC, Ferrari R, Munro J. Pre-formed articulating knee spacer in two-stage revision for the infected total knee arthroplasty. Int Orthop. 2005;29:305–308.PubMedCrossRefGoogle Scholar
- 28.Pitto RP, Spika IA. Antibiotic-loaded bone cement spacers in two-stage management of infected total knee arthroplasty. Int Orthop. 2004;28:129–133.PubMedCrossRefGoogle Scholar
- 29.Salgado C, Dash S, Cantey JR, Marculescu C. Higher risk of failure of methicillin-resistant Staphylococcus aureus prosthetic joint infections. Clin Orthop Relat Res. 2007;461:48–53.PubMedGoogle Scholar
- 30.Sculco TP. The economic impact of infected total joint arthroplasty. Instr Course Lect. 1993;42:349–351.PubMedGoogle Scholar
- 31.Volin S, Hinrichs S, Garvin K. Two-stage reimplantation of total joint infections: a comparison of resistant and non-resistant organisms. Clin Orthop Relat Res. 2004;427:94–100.PubMedCrossRefGoogle Scholar