Clinical Orthopaedics and Related Research®

, Volume 469, Issue 7, pp 2019–2027 | Cite as

Bizarre Parosteal Osteochondromatous Proliferation: A Locally Aggressive Benign Tumor

  • Jibu Joseph
  • David Ritchie
  • Elaine MacDuff
  • Ashish Mahendra
Clinical Research

Abstract

Background

Bizarre parosteal osteochondromatous proliferation (BPOP) is a benign lesion of bone, and numerous questions remain unresolved regarding its etiology, diagnosis, and treatment.

Questions/purposes

We present the Scottish Bone Tumour Registry experience of this rare lesion.

Patients and Methods

We performed a retrospective analysis of the Scottish Bone Tumour Registry records. Histologic specimens were reexamined by a musculoskeletal pathologist. Radiographs were reevaluated by a musculoskeletal radiologist.

Results

From 1983 to 2009, 13 cases (13 patients; six male, seven female) were identified. Their ages ranged from 13 to 65 years. All patients presented with localized swelling. Pain was present in five. Antecedent trauma was present in two. Nine lesions affected the hand, three the foot, and one the tibial tuberosity. Twelve lesions were excised and one was curetted. There were seven recurrences of which six were excised. One lesion recurred a second time and was excised. There were no metastases. Radiographs showed densely mineralized lesions contiguous with an uninvolved cortex. Cortical breakthrough was present in one case and scalloping in another. Histologic analysis characteristically showed hypercellular cartilage with pleomorphism and calcification/ossification without atypia, bone undergoing maturation, and a spindle cell stroma.

Conclusions

BPOP is a rare benign lesion that probably is neoplastic, with no gender predilection, and affecting patients over a wide age range. Previously trauma was considered an etiologic factor, but this no longer seems to be the case. The rate of recurrence was 50%, which may indicate a more extensive resection is required for this locally aggressive lesion. No metastases were reported. BPOP should not be mistaken for, or treated as, a malignant tumor.

Level of Evidence

Level IV, retrospective case series. See Guidelines for Authors for a complete description of levels of evidence.

Notes

Acknowledgment

We acknowledge the contribution to this study by Anand Pillai regarding collection of patient data.

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Copyright information

© The Association of Bone and Joint Surgeons® 2011

Authors and Affiliations

  • Jibu Joseph
    • 1
  • David Ritchie
    • 2
  • Elaine MacDuff
    • 3
  • Ashish Mahendra
    • 4
  1. 1.Department of Trauma and OrthopaedicsGlasgow Western InfirmaryGlasgowUK
  2. 2.Department of RadiologyGlasgow Western InfirmaryGlasgowUK
  3. 3.Department of PathologyGlasgow Western InfirmaryGlasgowUK
  4. 4.Department of Trauma and Orthopaedic SurgeryGlasgow Royal InfirmaryGlasgowUK

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