Clinical Orthopaedics and Related Research®

, Volume 468, Issue 3, pp 852–860 | Cite as

Allografting in Locked Nailing and Interfragmentary Wiring for Humeral Nonunions

  • Wei-Peng Lin
  • Jinn LinEmail author
Clinical Research


In this prospective study, we compared outcomes after repair of humeral nonunions when morsellized fresh-frozen allograft or autograft was used to augment repair by intramedullary nailing. Sixty-five patients with humeral shaft nonunions of greater than 6 months’ duration and gross instability at the nonunion site were included and treated by locked nailing, interfragmentary wiring, and bone grafting. Graft type was determined by patient preference. Outcomes assessed included union rate and functional recovery of the arm. Secondary end points included operative blood loss, operation time, hospital stay, time to fracture healing, and complications. Twenty-eight patients with autografts and 36 with allografts were followed up more than 2 years. The baseline conditions of the two groups were similar. The autograft group had greater blood loss and longer operative time than the allograft group. The autograft group also had a longer hospital stay. The healing rate, time to healing, and functional scores did not differ between these two groups. In the autograft group, 43% reported pain and limited mobility as a result of the donor site. We concluded that when used in association with locked nailing for humeral nonunions, allografts can achieve treatment results similar to autografts but without donor site complications.

Level of Evidence: Level III, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.


Graft Type Radial Nerve Palsy Mayo Elbow Performance Score Autograft Group Allograft Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We thank Shun-Min Zhang, MD, and Xian-Yang Hou, MD, for their efforts in patient evaluation and followup.

Supplementary material

Supplementary material 1 (MPG 3648 kb)


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Copyright information

© The Association of Bone and Joint Surgeons® 2009

Authors and Affiliations

  1. 1.Department of Orthopedic SurgeryNational Taiwan University HospitalTaipeiTaiwan

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