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Clinical Orthopaedics and Related Research

, Volume 466, Issue 7, pp 1710–1715 | Cite as

Periprosthetic Joint Infection: The Incidence, Timing, and Predisposing Factors

  • Luis Pulido
  • Elie Ghanem
  • Ashish Joshi
  • James J. Purtill
  • Javad Parvizi
Original Article Infection

Abstract

Periprosthetic joint infection is one of the most challenging complications of joint arthroplasty. We identified current risk factors of periprosthetic joint infection after modern joint arthroplasty, and determined the incidence and timing of periprosthetic joint infection. We reviewed prospectively collected data from our database on 9245 patients undergoing primary hip or knee arthroplasty between January 2001 and April 2006. Periprosthetic joint infections developed in 63 patients (0.7%). Sixty-five percent of periprosthetic joint infections developed within the first year of the index arthroplasty. The infecting organism was isolated in 57 of 63 cases (91%). The most common organisms identified were Staphylococcus aureus and Staphylococcus epidermidis. We identified the following independent predictors for periprosthetic joint infection: higher American Society of Anesthesiologists score, morbid obesity, bilateral arthroplasty, knee arthroplasty, allogenic transfusion, postoperative atrial fibrillation, myocardial infarction, urinary tract infection, and longer hospitalization. This study confirmed some previously implicated factors and identified new variables that predispose patients to periprosthetic joint infection.

Level of Evidence: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.

Keywords

Periprosthetic Joint Infection Postoperative Atrial Fibrillation Periprosthetic Infection Allogenic Transfusion Postoperative Urinary Tract Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Association of Bone and Joint Surgeons 2008

Authors and Affiliations

  • Luis Pulido
    • 1
  • Elie Ghanem
    • 1
  • Ashish Joshi
    • 1
  • James J. Purtill
    • 1
  • Javad Parvizi
    • 1
  1. 1.Rothman Institute of OrthopedicsThomas Jefferson University HospitalPhiladelphiaUSA

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