Medical therapy for cholesterol-gallstones: A role of statins?
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The combination of statin drugs with ursodiol for the dissolution of cholesterol gallstones may be more effective than monotherapy alone. Adding a statin drug that inhibits HMG-CoA reductase may reduce biliary cholesterol so that the combination with ursodiol produces the maximum decrease in biliary cholesterol secretion. The major disadvantage is the added cost of using two drugs.
KeywordsBile Acid Pravastatin Cholic Acid Ursodeoxycholic Acid Chenodeoxycholic Acid
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References and Recommended Reading
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