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Dietary fat quality and coronary heart disease prevention: A unified theory based on evolutionary, historical, global, and modern perspectives

  • Christopher E. Ramsden
  • Keturah R. Faurot
  • Pedro Carrera-Bastos
  • Loren Cordain
  • Michel De Lorgeril
  • Laurence S. Sperling
Article

Opinion statement

A large and growing body of evidence indicates that dietary fatty acids regulate crucial metabolic processes involved in the pathogenesis of coronary heart disease (CHD). Despite this evidence, optimal dietary fatty acid intakes for CHD prevention remain unclear. Significant gaps in the modern nutrition literature and contradictions in its interpretation have precluded broad consensus. These shortcomings can be addressed through the incorporation of evolutionary, historical, and global perspectives. The objective of this review is to propose a unified theory of optimal dietary fatty acid intake for CHD prevention that integrates critical insights from evolutionary, historical, global, and modern perspectives. This broad approach may be more likely than previous methods to characterize optimal fatty acid intakes.

Keywords

Coronary Heart Disease Trans Fatty Acid Coronary Heart Disease Risk Coronary Heart Disease Prevention Coronary Heart Disease Risk Reduction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Current Medicine Group, LLC 2009

Authors and Affiliations

  • Christopher E. Ramsden
    • 1
  • Keturah R. Faurot
  • Pedro Carrera-Bastos
  • Loren Cordain
  • Michel De Lorgeril
  • Laurence S. Sperling
  1. 1.Department of Physical Medicine and Rehabilitation, Program on Integrative MedicineUniversity of North Carolina-Chapel Hill School of MedicineChapel HillUSA

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