Current Urology Reports

, 20:56 | Cite as

Role of Positron Emission Tomography Imaging in Metabolically Active Renal Cell Carcinoma

  • Vidhya Karivedu
  • Amit L. Jain
  • Thomas J. Eluvathingal
  • Abhinav SidanaEmail author
New Imaging Techniques (S Rais-Bahrami and K Porter, Section Editors)
Part of the following topical collections:
  1. Topical Collection on New Imaging Techniques


Purpose of Review

The clinical role of fluorine-18 fluoro-2-deoxyglucose (FDG)-positron emission tomography (PET) in renal cell carcinoma (RCC) is still evolving. Use of FDG PET in RCC is currently not a standard investigation in the diagnosis and staging of RCC due to its renal excretion. This review focuses on the clinical role and current status of FDG PET and PET/CT in RCC.

Recent Findings

Studies investigating the role of FDG PET in localized RCC were largely disappointing. Several studies have demonstrated that the use of hybrid imaging PET/CT is feasible in evaluating the extra-renal disease. A current review of the literature determines PET/CT to be a valuable tool both in treatment decision-making and monitoring and in predicting the survival in recurrent and metastatic RCC.


PET/CT might be a viable option in the evaluation of RCC, especially recurrent and metastatic disease. PET/CT has also shown to play a role in predicting survival and monitoring therapy response.


Fluorodeoxyglucose (FDG) Positron emission tomography/computed tomography (PET/CT) Metabolically active renal cell carcinoma Restaging Metastases Therapy monitoring 


Compliance with Ethical Standards

Conflict of Interest

Vidhya Karivedu, Amit L Jain, Thomas J. Eluvathingal, and Abhinav Sidana each declare no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Vidhya Karivedu
    • 1
  • Amit L. Jain
    • 2
  • Thomas J. Eluvathingal
    • 3
  • Abhinav Sidana
    • 4
    • 5
    Email author
  1. 1.Department of Internal Medicine, Division of Medical OncologyThe Ohio State UniversityColumbusUSA
  2. 2.Department of Internal MedicineUniversity of Tennessee Health Science CenterMemphisUSA
  3. 3.Department of RadiologyUniversity of CincinnatiCincinnatiUSA
  4. 4.Division of UrologyUniversity of CincinnatiCincinnatiUSA
  5. 5.Division of Urology, University of Cincinnati Cancer InstituteUniversity of Cincinnati College of MedicineCincinnatiUSA

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