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Current Urology Reports

, 15:446 | Cite as

Surgical Management of Peyronie’s Disease

  • Uwais B. Zaid
  • Amjad Alwaal
  • Xiaoyu Zhang
  • Tom F. Lue
Men's Health (R Carrion and C Yang, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Men’s Health

Abstract

Peyronie’s disease (PD) has a significant impact on the quality of life of both patients and their partners due to the compromised sexual function and physical deformation resulting from the condition. PD is a connective tissue disorder marked by fibrotic healing of the tunica albuginea, leading to penile deformities including curvature, shortening, loss of girth, hourglass appearance, and hinging. Despite the multiple medical therapies available, surgery is the gold standard of treatment once the plaque has stabilized. We present a review of the disease process, preoperative evaluation, operative planning, surgical treatments with outcomes and complications, and nascent developments in surgical management and graft development. Options include tunical lengthening procedures, tunical shortening procedures, and penile prosthesis. Decision-making is governed by degree of curvature, erectile function, and associated penile deformities. In cases with curvature of less than 60–70 degrees, adequate penile length, and no hourglass deformity, patients are candidates for tunical shortening procedures. Patients with curvature greater than 60–70 degrees, penile hourglass or hinge-destabilizing deformities, and adequate erectile function should be counseled with regard to tunical lengthening procedures. Patients with poor preoperative erectile function should undergo inflatable penile prosthesis placement, with possible secondary straightening procedures. Technique selection should be based upon surgeon preference, expertise, and experience, as evidence does not necessarily support one procedure over another.

Keywords

Peyronie’s disease Surgical management Penile prosthesis Tunical shortening 

Notes

Compliance with Ethics Guidelines

Conflict of Interest

Dr. Uwais B. Zaid, Dr. Amjad Alwaal, Dr. Xiaoyu Zhang, and Dr. Tom F. Lue each declare no potential conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. 1.•
    Nelson CJ, Mulhall JP. Psychological impact of Peyronie's disease: A review. J Sex Med. 2013;10(3):653–60. Excellent review of the physiology and psychological impact of Peyronie’s disease.PubMedCrossRefGoogle Scholar
  2. 2.•
    Levine LA, Larsen SM. Surgery for Peyronie's disease. Asian J Androl. 2013;15(1):27–34. Excellent review of treatments and pathophysiology of Peyronie’s disease.PubMedPubMedCentralCrossRefGoogle Scholar
  3. 3.•
    Ralph D, Gonzalez-Cadavid N, Mirone V, et al. The management of Peyronie's disease: Evidence-based 2010 guidelines. J Sex Med. 2010;7(7):2359–74. Excellent evidenced-based review of treatment options.PubMedGoogle Scholar
  4. 4.
    Nugteren HM, Nijman JM, de Jong IJ, van Driel MF. The association between Peyronie's and Dupuytren's disease. Int J Impot Res. 2011;23(4):142–5.PubMedCrossRefGoogle Scholar
  5. 5.
    Dibenedetti DB, Nguyen D, Zografos L, Ziemiecki R, Zhou X. A Population-Based Study of Peyronie's Disease: Prevalence and Treatment Patterns in the United States. Adv Urol. 2011; 282503.Google Scholar
  6. 6.
    Carson CC, Levine LA. Outcomes of Surgical Treatment of Peyronie's Disease. BJU Int. 2013.Google Scholar
  7. 7.
    Garaffa G, Trost LW, Serefoglu EC, Ralph D, Hellstrom WJ. Understanding the course of Peyronie's disease. Int J Clin Pract. 2013;67(8):781–8.PubMedCrossRefGoogle Scholar
  8. 8.
    Tal R, Heck M, Teloken P, Siegrist T, Nelson CJ, Mulhall JP. Peyronie's disease following radical prostatectomy: Incidence and predictors. J Sex Med. 2010;7(3):1254–61.PubMedCrossRefGoogle Scholar
  9. 9.
    El-Sakka AI, Tayeb KA. Peyronie's disease in diabetic patients being screened for erectile dysfunction. J Urol. 2005;174(3):1026–30.PubMedCrossRefGoogle Scholar
  10. 10.
    El-Sakka AI, Hassoba HM, Chui RM, Bhatnagar RS, Dahiya R, Lue TF. An animal model of Peyronie's-like condition associated with an increase of transforming growth factor beta mRNA and protein expression. J Urol. 1997;158(6):2284–90.PubMedCrossRefGoogle Scholar
  11. 11.
    Ryu JK, Piao S, Shin HY, et al. IN-1130, a novel transforming growth factor-beta type I receptor kinase (activin receptor-like kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease. J Sex Med. 2009;6(5):1284–96.PubMedCrossRefGoogle Scholar
  12. 12.
    El-Sakka AI, Hassoba HM, Pillarisetty RJ, Dahiya R, Lue TF. Peyronie's disease is associated with an increase in transforming growth factor-beta protein expression. J Urol. 1997;158(4):1391–4.PubMedCrossRefGoogle Scholar
  13. 13.
    Bivalacqua TJ, Diner EK, Novak TE, Vohra Y, Sikka SC, Champion HC, et al. A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression. J Urol. 2000;163(6):1992–8.PubMedCrossRefGoogle Scholar
  14. 14.
    Gonzalez-Cadavid NF. Mechanisms of penile fibrosis. J Sex Med. 2009;6 Suppl 3:353–62.PubMedCrossRefGoogle Scholar
  15. 15.
    Kadioglu A, Tefekli A, Erol B, Oktar T, Tunc M, Tellaloglu S. A retrospective review of 307 men with Peyronie's disease. J Urol. 2002;168(3):1075–9.PubMedCrossRefGoogle Scholar
  16. 16.
    Mulhall JP, Schiff J, Guhring P. An Analysis of the Natural History of Peyronie’s Disease. J Urol. 2006;175(6):2115–8.PubMedCrossRefGoogle Scholar
  17. 17.
    Serefoglu EC, Hellstrom WJ. Treatment of Peyronie's disease: 2012 update. Curr Urol Rep. 2011;12(6):444–52.PubMedCrossRefGoogle Scholar
  18. 18.
    Martinez D, Ercole CE, Hakky TS, Kramer A, Carrion R. Peyronie's Disease: Still a Surgical Disease. Adv Urol. 2012;2012:206284.PubMedPubMedCentralCrossRefGoogle Scholar
  19. 19.
    Segal RL, Burnett AL. Surgical Management for Peyronie's Disease. World J Men's Health. 2013;31(1):1–11.CrossRefGoogle Scholar
  20. 20.
    Kendirci M, Hellstrom WJ. Critical analysis of surgery for Peyronie's disease. Curr Opin Urol. 2004;14(6):381–8.PubMedCrossRefGoogle Scholar
  21. 21.
    Levine LA, Burnett AL. Standard operating procedures for Peyronie's disease. J Sex Med. 2013;10(1):230–44.PubMedCrossRefGoogle Scholar
  22. 22.
    Fausto de Souza D, Micaelo L, Cuzzi T, Ramos-E-Silva M. Ledderhose disease: An unusual presentation. J Clin Aesth Dermatol. 2010;3(9):45–7.Google Scholar
  23. 23.
    Gholami SS, Gonzalez-Cadavid NF, Lin CS, Rajfer J, Lue TF. Peyronie's disease: A review. J Urol. 2003;169(4):1234–41.PubMedCrossRefGoogle Scholar
  24. 24.
    Bacal V, Rumohr J, Sturm R, Lipshultz LI, Schumacher M, Grober ED. Correlation of degree of penile curvature between patient estimates and objective measures among men with Peyronie's disease. J Sex Med. 2009;6(3):862–5.PubMedCrossRefGoogle Scholar
  25. 25.
    Ohebshalom M, Mulhall J, Guhring P, Parker M. Measurement of penile curvature in Peyronie's disease patients: Comparison of three methods. J Sex Med. 2007;4(1):199–203.PubMedCrossRefGoogle Scholar
  26. 26.
    Levine LA, Greenfield JM. Establishing a standardized evaluation of the man with Peyronie's disease. Int J Impot Res. 2003;15 Suppl 5:S103–12.PubMedCrossRefGoogle Scholar
  27. 27.
    Hellstrom WJ, Feldman R, Rosen RC, Smith T, Kaufman G, Tursi J. Bother and distress associated with Peyronie's disease: Validation of the Peyronie's disease questionnaire. J Urol. 2013;190(2):627–34.PubMedCrossRefGoogle Scholar
  28. 28.
    Wessells H, Lue TF, McAninch JW. Penile length in the flaccid and erect states: Guidelines for penile augmentation. J Urol. 1996;156(3):995–7.PubMedCrossRefGoogle Scholar
  29. 29.
    Kalokairinou K, Konstantinidis C, Domazou M, Kalogeropoulos T, Kosmidis P, Gekas A. US imaging in Peyronie's disease. J Clin Imaging Sci. 2012;2:63–7514.103053.PubMedPubMedCentralCrossRefGoogle Scholar
  30. 30.
    Levine L, Rybak J, Corder C, Farrel MR. Peyronie's Disease Plaque Calcification-Prevalence, Time to Identification, and Development of a New Grading Classification. J Sex Med. 2013.Google Scholar
  31. 31.
    Kadioglu A, Akman T, Sanli O, Gurkan L, Cakan M, Celtik M. Surgical treatment of Peyronie's disease: A critical analysis. Eur Urol. 2006;50(2):235–48.PubMedCrossRefGoogle Scholar
  32. 32.
    Chung E, Clendinning E, Lessard L, Brock G. Five-year follow-up of Peyronie's graft surgery: Outcomes and patient satisfaction. J Sex Med. 2011;8(2):594–600.PubMedCrossRefGoogle Scholar
  33. 33.
    Mulhall J, Anderson M, Parker M. A surgical algorithm for men with combined Peyronie's disease and erectile dysfunction: Functional and satisfaction outcomes. J Sex Med. 2005;2(1):132–8.PubMedCrossRefGoogle Scholar
  34. 34.
    Levine LA, Lenting EL. A surgical algorithm for the treatment of Peyronie's disease. J Urol. 1997;158(6):2149–52.PubMedCrossRefGoogle Scholar
  35. 35.
    Taylor FL, Abern MR, Levine LA. Predicting erectile dysfunction following surgical correction of Peyronie's disease without inflatable penile prosthesis placement: Vascular assessment and preoperative risk factors. J Sex Med. 2012;9(1):296–301.PubMedCrossRefGoogle Scholar
  36. 36.
    Flores S, Choi J, Alex B, Mulhall JP. Erectile dysfunction after plaque incision and grafting: Short-term assessment of incidence and predictors. J Sex Med. 2011;8(7):2031–7.PubMedCrossRefGoogle Scholar
  37. 37.
    Levine LA, Dimitriou RJ. A surgical algorithm for penile prosthesis placement in men with erectile failure and Peyronie's disease. Int J Impot Res. 2000;12(3):147–51.PubMedCrossRefGoogle Scholar
  38. 38.
    Wilson SK, Delk 2nd JR. A new treatment for Peyronie's disease: Modeling the penis over an inflatable penile prosthesis. J Urol. 1994;152(4):1121–3.PubMedGoogle Scholar
  39. 39.
    Savoca G, Scieri F, Pietropaolo F, Garaffa G, Belgrano E. Straightening corporoplasty for Peyronie's disease: A review of 218 patients with median follow-up of 89 months. Eur Urol. 2004;46(5):610–4. discussion 613-614.PubMedCrossRefGoogle Scholar
  40. 40.
    Bokarica P, Parazajder J, Mazuran B, Gilja I. Surgical treatment of Peyronie's disease based on penile length and degree of curvature. Int J Impot Res. 2005;17(2):170–4.PubMedCrossRefGoogle Scholar
  41. 41.
    Syed AH, Abbasi Z, Hargreave TB. Nesbit procedure for disabling Peyronie’s curvature: A median follow-up of 84 months. Urology. 2003;61(5):999–1003.PubMedCrossRefGoogle Scholar
  42. 42.
    Ralph DJ, Al-Akraa M, Pryor JP. The nesbit operation for Peyronie's disease: 16-year experience. J Urol. 1995;154(4):1362–3.PubMedCrossRefGoogle Scholar
  43. 43.
    Licht MR, Lewis RW. Modified nesbit procedure for the treatment of Peyronie's disease: A comparative outcome analysis. J Urol. 1997;158(2):460–3.PubMedCrossRefGoogle Scholar
  44. 44.
    Yachia D. Modified corporoplasty for the treatment of penile curvature. J Urol. 1990;143(1):80–2.PubMedGoogle Scholar
  45. 45.
    Daitch JA, Angermeier KW, Montague DK. Modified corporoplasty for penile curvature: Long-term results and patient satisfaction. J Urol. 1999;162(6):2006–9.PubMedCrossRefGoogle Scholar
  46. 46.
    Rehman J, Benet A, Minsky LS, Melman A. Results of surgical treatment for abnormal penile curvature: Peyronie's disease and congenital deviation by modified nesbit plication (tunical shaving and plication). J Urol. 1997;157(4):1288–91.PubMedCrossRefGoogle Scholar
  47. 47.
    Mufti GR, Aitchison M, Bramwell SP, Paterson PJ, Scott R. Corporeal plication for surgical correction of Peyronie's disease. J Urol. 1990;144(2 Pt 1):281–2. discussion 283.PubMedGoogle Scholar
  48. 48.
    Giammusso B, Burrello M, Branchina A, Nicolosi F, Motta M. Modified corporoplasty for ventral penile curvature: Description of the technique and initial results. J Urol. 2004;171(3):1209–11.PubMedCrossRefGoogle Scholar
  49. 49.
    Lopes I, Tomada N, Vendeira P. Penile corporoplasty with Yachia's technique for Peyronie's disease: Single center experience with 117 patients. Urol Ann. 2013;5(3):167–71.PubMedPubMedCentralCrossRefGoogle Scholar
  50. 50.
    Gholami SS, Lue TF. Correction of penile curvature using the 16-dot plication technique: A review of 132 patients. J Urol. 2002;167(5):2066–9.PubMedCrossRefGoogle Scholar
  51. 51.
    Chahal R, Gogoi NK, Sundaram SK, Weston PM. Corporal plication for penile curvature caused by Peyronie's disease: The patients' perspective. BJU Int. 2001;87(4):352–6.PubMedCrossRefGoogle Scholar
  52. 52.
    Geertsen UA, Brok KE, Andersen B, Nielsen HV. Peyronie curvature treated by plication of the penile fasciae. Br J Urol. 1996;77(5):733–5.PubMedCrossRefGoogle Scholar
  53. 53.
    Thiounn N, Missirliu A, Zerbib M, Larrouy M, Dje K, Flam T, et al. Corporeal plication for surgical correction of penile curvature. experience with 60 patients. Eur Urol. 1998;33(4):401–4.PubMedCrossRefGoogle Scholar
  54. 54.
    Van Der Horst C, Martinez Portillo FJ, Seif C, Alken P, Juenemann KP. Treatment of penile curvature with Essed-Schroder tunical plication: Aspects of quality of life from the patients' perspective. BJU Int. 2004;93(1):105–8.CrossRefGoogle Scholar
  55. 55.
    Schultheiss D, Meschi MR, Hagemann J, Truss MC, Stief CG, Jonas U. Congenital and acquired penile deviation treated with the Essed plication method. Eur Urol. 2000;38(2):167–71.PubMedCrossRefGoogle Scholar
  56. 56.
    Dugi 3rd DD, Morey AF. Penoscrotal plication as a uniform approach to reconstruction of penile curvature. BJU Int. 2010;105(10):1440–4.PubMedCrossRefGoogle Scholar
  57. 57.
    Paez A, Mejias J, Vallejo J, Romero I, De Castro M, Gimeno F, et al. Long-term patient satisfaction after surgical correction of penile curvature via tunical plication. Int Braz J Urol Off J Braz Soc Urol. 2007;33(4):502–7. discussion 507-9.CrossRefGoogle Scholar
  58. 58.
    Kadioglu A, Sanli O, Akman T, Cakan M, Erol B, Mamadov F. Surgical treatment of Peyronie's disease: A single center experience with 145 patients. Eur Urol. 2008;53(2):432–9.PubMedCrossRefGoogle Scholar
  59. 59.
    Iacono F, Prezioso D, Ruffo A, Illiano E, Romeo G, Amato B. Tunical plication in the management of penile curvature due La Peyronie's disease. Our experience on 47 cases. BMC Surgery. 2012;12 Suppl 1:S25.PubMedPubMedCentralCrossRefGoogle Scholar
  60. 60.
    Hudak SJ, Morey AF, Adibi M, Bagrodia A. Favorable patient reported outcomes after penile plication for wide array of Peyronie disease abnormalities. J Urol. 2013;189(3):1019–24.PubMedCrossRefGoogle Scholar
  61. 61.
    Andrews HO, al-Akraa M, Pryor JP, Ralph DJ. The nesbit operation for congenital curvature of the penis. Int J Impot Res. 1999;11(3):119–22.PubMedCrossRefGoogle Scholar
  62. 62.
    Tornehl CK, Carson CC. Surgical alternatives for treating Peyronie's disease. BJU Int. 2004;94(6):774–83.PubMedCrossRefGoogle Scholar
  63. 63.
    Schwarzer JU, Steinfatt H. Tunica albuginea underlap–a new modification of the Nesbit procedure: Description of the technique and preliminary results. J Sex Med. 2012;9(11):2970–4.PubMedCrossRefGoogle Scholar
  64. 64.
    Donatucci CF, Lue TF. Correction of penile deformity assisted by intracavernous injection of papaverine. J Urol. 1992;147(4):1108–10.PubMedGoogle Scholar
  65. 65.
    Adibi M, Hudak SJ, Morey AF. Penile plication without degloving enables effective correction of complex Peyronie's deformities. Urology. 2012;79(4):831–5.PubMedCrossRefGoogle Scholar
  66. 66.
    Parker J, Martinez D, Hakky T, Carrion R. Minimally Invasive Modification of the Dot Plication Technique Utilizing Absorbable Sutures. J Sex Med. 2012;9 suppl 4:183–298.Google Scholar
  67. 67.
    Brant WO, Bella AJ, Lue TF. 16-dot procedure for penile curvature. J Sex Med. 2007;4(2):277–80.PubMedCrossRefGoogle Scholar
  68. 68.
    Dalkin BL, Carter MF. Venogenic impotence following dermal graft repair for Peyronie's disease. J Urol. 1991;146(3):849–51.PubMedGoogle Scholar
  69. 69.
    Gelbard MK. Relaxing incisions in the correction of penile deformity due to Peyronie's disease. J Urol. 1995;154(4):1457–60.PubMedCrossRefGoogle Scholar
  70. 70.
    Lue TF, El-Sakka A. I. Venous patch graft for Peyronie's disease. part I: Technique. J Urol. 1998;160(6 Pt 1):2047–9.PubMedGoogle Scholar
  71. 71.
    Austoni E, Colombo F, Romano AL, Guarneri A, Kartalas Goumas I, Cazzaniga A. Soft prosthesis implant and relaxing albugineal incision with saphenous grafting for surgical therapy of Peyronie's disease: A 5-year experience and long-term follow-up on 145 operated patients. Eur Urol. 2005;47(2):223–9. discussion 229.PubMedCrossRefGoogle Scholar
  72. 72.
    Zucchi A, Silvani M, Pecoraro S. Corporoplasty with small soft axial prostheses (VIRILIS I(R)) and bovine pericardial graft (HYDRIX(R)) in Peyronie's disease. Asian J Androl. 2013;15(2):275–9.PubMedPubMedCentralCrossRefGoogle Scholar
  73. 73.
    Levine LA. Partial plaque excision and grafting (PEG) for Peyronie's disease. J Sex Med. 2011;8(7):1842–5.PubMedCrossRefGoogle Scholar
  74. 74.
    Egydio PH, Lucon AM, Arap S. A single relaxing incision to correct different types of penile curvature: Surgical technique based on geometrical principles. BJU Int. 2004;94(7):1147–57.PubMedCrossRefGoogle Scholar
  75. 75.
    Rybak J, Papagiannopoulos D, Levine L. A retrospective comparative study of traction therapy vs no traction following tunica albuginea plication or partial excision and grafting for Peyronie's disease: Measured lengths and patient perceptions. J Sex Med. 2012;9(9):2396–403.PubMedCrossRefGoogle Scholar
  76. 76.
    Chun JL, McGregor A, Krishnan R, Carson CC. A comparison of dermal and cadaveric pericardial grafts in the modified horton-devine procedure for Peyronie's disease. J Urol. 2001;166(1):185–8.PubMedCrossRefGoogle Scholar
  77. 77.
    Carson CC, Chun JL. Peyronie's disease: Surgical management: Autologous materials. Int J Impot Res. 2002;14(5):329–35.PubMedCrossRefGoogle Scholar
  78. 78.
    Brannigan RE, Kim ED, Oyasu R, McVary KT. Comparison of tunica albuginea substitutes for the treatment of Peyronie's disease. J Urol. 1998;159(3):1064–8.PubMedCrossRefGoogle Scholar
  79. 79.
    Hellstrom WJ, Reddy S. Application of pericardial graft in the surgical management of Peyronie's disease. J Urol. 2000;163(5):1445–7.PubMedCrossRefGoogle Scholar
  80. 80.
    Knoll LD. Use of small intestinal submucosa graft for the surgical management of Peyronie's disease. J Urol. 2007;178(6):2474–8. discussion 2478.PubMedCrossRefGoogle Scholar
  81. 81.
    Brock G, Kadioglu A, Lue TF. Peyronie's disease: A modified treatment. Urology. 1993;42(3):300–4.PubMedCrossRefGoogle Scholar
  82. 82.
    Kalsi J, Minhas S, Christopher N, Ralph D. The results of plaque incision and venous grafting (Lue procedure) to correct the penile deformity of Peyronie's disease. BJU Int. 2005;95(7):1029–33.PubMedCrossRefGoogle Scholar
  83. 83.
    Adeniyi AA, Goorney SR, Pryor JP, Ralph DJ. The Lue procedure: An analysis of the outcome in Peyronie's disease. BJU Int. 2002;89(4):404–8.PubMedCrossRefGoogle Scholar
  84. 84.
    Montorsi F, Salonia A, Maga T, Bua L, Guazzoni G, Barbieri L, et al. Evidence based assessment of long-term results of plaque incision and vein grafting for Peyronie's disease. J Urol. 2000;163(6):1704–8.PubMedCrossRefGoogle Scholar
  85. 85.
    De Stefani S, Savoca G, Ciampalini S, Gattuccio I, Scieri F, Belgrano E. Saphenous vein harvesting by 'stripping' technique and 'W'-shaped patch covering after plaque incision in treatment of Peyronie's disease. Int J Impot Res. 2000;12(6):299–301.PubMedCrossRefGoogle Scholar
  86. 86.
    Yurkanin JP, Dean R, Wessells H. Effect of incision and saphenous vein grafting for Peyronie's disease on penile length and sexual satisfaction. J Urol. 2001;166(5):1769–72. discussion 1772-3.PubMedCrossRefGoogle Scholar
  87. 87.
    Kim DH, Lesser TF, Aboseif SR. Subjective patient-reported experiences after surgery for Peyronie's disease: Corporeal plication versus plaque incision with vein graft. Urology. 2008;71(4):698–702.PubMedCrossRefGoogle Scholar
  88. 88.
    Cormio L, Zucchi A, Lorusso F, et al. Surgical treatment of Peyronie's disease by plaque incision and grafting with buccal mucosa. Eur Urol. 2009;55(6):1469–75.PubMedCrossRefGoogle Scholar
  89. 89.
    Shioshvili TJ, Kakonashvili AP. The surgical treatment of Peyronie's disease: Replacement of plaque by free autograft of buccal mucosa. Eur Urol. 2005;48(1):129–33. discussion 134-125.PubMedCrossRefGoogle Scholar
  90. 90.
    Kargi E, Yesilli C, Hosnuter M, Akduman B, Babuccu O, Mungan A. Relaxation incision and fascia lata grafting in the surgical correction of penile curvature in Peyronie's disease. Plast Reconstr Surg. 2004;113(1):254–9.PubMedCrossRefGoogle Scholar
  91. 91.
    Kalsi JS, Christopher N, Ralph DJ, Minhas S. Plaque incision and fascia lata grafting in the surgical management of Peyronie's disease. BJU Int. 2006;98(1):110–4. discussion 114-5.PubMedCrossRefGoogle Scholar
  92. 92.
    Kalsi JS, Christopher N, Ralph DJ, Minhas S. Plaque incision and fascia lata grafting in the surgical management of Peyronie's disease. BJU Int. 2006;98(1):110–4. discussion 114-115.PubMedCrossRefGoogle Scholar
  93. 93.
    Sampaio JS, Fonseca J, Passarinho A, Cristino J, Mendes J. Peyronie's disease: Surgical correction of 40 patients with relaxing incision and dura mater graft. Eur Urol. 2002;41(5):551–5.PubMedCrossRefGoogle Scholar
  94. 94.
    Fallon B. Cadaveric dura mater graft for correction of penile curvature in Peyronie disease. Urology. 1990;35(2):127–9.PubMedCrossRefGoogle Scholar
  95. 95.
    Craatz S, Spanel-Borowski K, Begemann JF, Olianas R, Fisch M, Hohenfellner R. The dorsal lamina of the rectus sheath: A suitable grafting material for the penile tunica albuginea in Peyronie's disease? BJU Int. 2006;97(1):134–7.PubMedCrossRefGoogle Scholar
  96. 96.
    Taylor FL, Levine LA. Surgical correction of Peyronie's disease via tunica albuginea plication or partial plaque excision with pericardial graft: Long-term follow up. J Sex Med. 2008;5(9):2221–8. discussion 2229-2230.PubMedCrossRefGoogle Scholar
  97. 97.
    Kovac JR, Brock GB. Surgical outcomes and patient satisfaction after dermal, pericardial, and small intestinal submucosal grafting for Peyronie's disease. J Sex Med. 2007;4(5):1500–8.PubMedCrossRefGoogle Scholar
  98. 98.
    Lee EW, Shindel AW, Brandes SB. Small intestinal submucosa for patch grafting after plaque incision in the treatment of Peyronie's disease. Int Braz J Urol Off J Braz Soc Urol. 2008;34(2):191–6. discussion 197.CrossRefGoogle Scholar
  99. 99.
    Breyer BN, Brant WO, Garcia MM, Bella AJ, Lue TF. Complications of porcine small intestine submucosa graft for Peyronie's disease. J Urol. 2007;177(2):589–91.PubMedCrossRefGoogle Scholar
  100. 100.
    Staerman F, Pierrevelcin J, Ripert T, Menard J. Medium-term follow-up of plaque incision and porcine small intestinal submucosal grafting for Peyronie's disease. Int J Impot Res. 2010;22(6):343–8.PubMedCrossRefGoogle Scholar
  101. 101.
    Lentz AC, Carson 3rd CC. Peyronie's surgery: Graft choices and outcomes. Curr Urol Rep. 2009;10(6):460–7.PubMedCrossRefGoogle Scholar
  102. 102.
    Hatzichristodoulou G, Gschwend JE, Lahme S. Surgical therapy of Peyronie's disease by partial plaque excision and grafting with collagen fleece: Feasibility study of a new technique. Int J Impot Res. 2013;25(5):183–7.PubMedCrossRefGoogle Scholar
  103. 103.
    Ferretti L, Giuliani M, Bessede T, et al. Tissue engineering for penile surgery: Comparative study of noncellular and cell-seeded synthetic grafts for tunica albuginea replacement. J Sex Med. 2012;9(2):625–31.PubMedCrossRefGoogle Scholar
  104. 104.
    Imbeault A, Bernard G, Ouellet G, Bouhout S, Carrier S, Bolduc S. Surgical option for the correction of Peyronie's disease: An autologous tissue-engineered endothelialized graft. J Sex Med. 2011;8(11):3227–35.PubMedCrossRefGoogle Scholar
  105. 105.
    Ma L, Yang Y, Sikka SC, Kadowitz PJ, Ignarro LJ, Abdel-Mageed AB, et al. Adipose tissue-derived stem cell-seeded small intestinal submucosa for tunica albuginea grafting and reconstruction. PNAS. 2012;109(6):2090–5.PubMedPubMedCentralCrossRefGoogle Scholar
  106. 106.
    Montorsi F, Guazzoni G, Bergamaschi F, Rigatti P. Patient-partner satisfaction with semirigid penile prostheses for Peyronie's disease: A 5-year followup study. J Urol. 1993;150(6):1819–21.PubMedGoogle Scholar
  107. 107.
    Chung E, Solomon M, Deyoung L, Brock GB. Comparison between AMS 700 CX and Coloplast Titan Inflatable Penile Prosthesis for Peyronie's Disease Treatment and Remodeling: Clinical Outcomes and Patient Satisfaction. J Sex Med. 2012.Google Scholar
  108. 108.
    Wang R, Howard GE, Hoang A, Yuan JH, Lin HC, Dai YT. Prospective and long-term evaluation of erect penile length obtained with inflatable penile prosthesis to that induced by intracavernosal injection. Asian J Androl. 2009;11(4):411–5.PubMedPubMedCentralCrossRefGoogle Scholar
  109. 109.
    Egydio PH, Kuehhas FE, Sansalone S. Penile length and girth restoration in severe Peyronie's disease using circular and longitudinal grafting. BJU Int. 2013;111(4 Pt B):E213–9.PubMedCrossRefGoogle Scholar
  110. 110.
    Sansalone S, Garaffa G, Djinovic R, et al. Simultaneous penile lengthening and penile prosthesis implantation in patients with Peyronie's disease, refractory erectile dysfunction, and severe penile shortening. J Sex Med. 2012;9(1):316–21.PubMedCrossRefGoogle Scholar
  111. 111.
    Garaffa G, Minervini A, Christopher NA, Minhas S, Ralph DJ. The management of residual curvature after penile prosthesis implantation in men with Peyronie's disease. BJU Int. 2011;108(7):1152–6.PubMedCrossRefGoogle Scholar
  112. 112.
    DiBlasio CJ, Kurta JM, Botta S, et al. Peyronie's disease compromises the durability and component-malfunction rates in patients implanted with an inflatable penile prosthesis. BJU Int. 2010;106(5):691–4.PubMedCrossRefGoogle Scholar
  113. 113.
    Chaudhary M, Sheikh N, Asterling S, Ahmad I, Greene D. Peyronie's disease with erectile dysfunction: Penile modeling over inflatable penile prostheses. Urology. 2005;65(4):760–4.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Uwais B. Zaid
    • 1
  • Amjad Alwaal
    • 1
  • Xiaoyu Zhang
    • 1
  • Tom F. Lue
    • 1
  1. 1.Department of UrologyUCSF School of MedicineSan FranciscoUSA

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