Current Urology Reports

, Volume 14, Issue 2, pp 102–108

Conservative Nephron-Sparing Treatment of Upper-Tract Tumors

Urothelial Cancer (A Sagalowsky, Section Editor)

DOI: 10.1007/s11934-013-0305-1

Cite this article as:
Smith, P., Mandel, J. & Raman, J.D. Curr Urol Rep (2013) 14: 102. doi:10.1007/s11934-013-0305-1


While radical nephroureterectomy represents the gold standard for managing upper-tract urothelial carcinoma, nephron-sparing approaches have increasingly been utilized in the elective setting. Such considerations are accentuated by contemporary studies highlighting sequelae related to chronic kidney disease following nephrectomy. Kidney sparing treatments including segmental ureteral resection and endoscopic ablation may therefore be appropriate in select patients with small, solitary, low-grade upper-tract tumors. Bladder and ipsilateral upper-tract recurrences are frequent after nephron-sparing treatments for UTUC, thereby underscoring the need to maintain strict radiographic and endoscopic surveillance protocols in patients amenable to this rigorous compliance program.


Endoscopy Ureteroscopy Percutaneous Segmental ureteral resection Topical therapy 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Division of UrologyPenn State Milton S. Hershey Medical CenterHersheyUSA

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