Current Urology Reports

, Volume 11, Issue 1, pp 15–21 | Cite as

Management of Locally Recurrent Kidney Cancer



Locally recurrent kidney cancer is an uncommon but complicated problem. Due to the recognition of the importance of renal preservation and an increase in the use of nephron-sparing approaches via surgery or ablation, locally recurrent disease is being encountered with greater frequency. Treatments for locally recurrent kidney cancer include radical nephrectomy, repeat or salvage partial nephrectomy, de novo or repeat ablation, observation, or experimental systemic therapy. Each of these options has its own constellation of risks and benefits. When local recurrence is detected, the majority of renal units may be saved, but this often comes at the expense of higher perioperative complication rates, which rise with the number of previous interventions on the ipsilateral kidney. Extensive preoperative patient counseling is required to properly individualize therapy. Referral to a center of excellence should be considered before attempting repeat or salvage renal surgery.


Kidney cancer Recurrent kidney cancer Multifocal kidney cancer Partial nephrectomy Repeat renal surgery Salvage partial nephrectomy Ablation 



This research was supported by the Intramural Research Program of the NIH, National Cancer Institute, Center for Cancer Research.


No potential conflicts of interest relevant to this article were reported.


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Copyright information

© US Government 2010

Authors and Affiliations

  1. 1.Urologic Oncology Branch, National Cancer InstituteNational Institutes of HealthBethesdaUSA

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