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Female Sexual Dysfunction as a Warning Sign of Chronic Disease Development

  • Vincenza Di Stasi
  • Nunzia Verde
  • Elisa Maseroli
  • Irene Scavello
  • Sarah Cipriani
  • Tommaso Todisco
  • Mario Maggi
  • Linda VignozziEmail author
Female Sexual Dysfunction and Disorders (T Lorenz & R Nappi, Section Editors)
  • 18 Downloads
Part of the following topical collections:
  1. Topical Collection on Female Sexual Dysfunction and Disorders

Abstract

Purpose of Review

Female sexual dysfunctions (FSD) in chronic diseases are often multi-factorial, integrating several bio-psychological and socio-environmental components. The aim of this review is to summarize existing evidence on the association between the most common chronic conditions and FSD and also to frame systematically experimental findings into a comprehensive overview on candidate mechanisms through which chronic diseases drive FSD pathogenesis.

Recent Findings

In men, it is now clear that several chronic diseases favour the development of sexual dysfunction (SD), especially erectile dysfunction (ED), by an integration of multiple pathogenic factors. More importantly, in men, ED has been recognized as a harbinger of several serious underlying medical conditions, including the cardiovascular ones. Conversely, the nature of the relationship between SD and chronic diseases in women remains controversial and, in contrast to the well-established associations with ED in men, FSD is not yet acknowledged as a warning sign of other systemic diseases. In this review of literature, we try to demonstrate that this is changing because there are some clinical and research evidences about the importance to recognize FSD in chronic disease. Specifically, we summarize the recent findings about the relation between cardio-metabolic, respiratory, renal, neurologic and rheumatic diseases and FSD.

Summary

Management of FSD is an important task to improve the overall quality of life of patients suffering from chronic, longstanding and often progressive diseases. It is also possible that sexual symptoms might be a warning sign for unrecognized conditions, although this is far to be completely understood. Further studies are needed to fully understand and treat this emerging topic in specific clinical settings.

Keywords

Female sexuality Chronic diseases Gender medicine 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

All reported studies with human performed by the authors have been previously published and complied with all applicable ethical standards (including the Helsinki Declaration and its amendments, institutional/national research committee standards and international/national/institutional guidelines).

References

Papers of particular interest, published recently, have been highlighted as: • Of importance

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Vincenza Di Stasi
    • 1
    • 2
  • Nunzia Verde
    • 3
  • Elisa Maseroli
    • 1
    • 2
  • Irene Scavello
    • 1
    • 2
  • Sarah Cipriani
    • 1
    • 2
  • Tommaso Todisco
    • 1
    • 2
  • Mario Maggi
    • 1
    • 4
    • 5
  • Linda Vignozzi
    • 1
    • 2
    • 5
    Email author
  1. 1.Department of Experimental, Clinical, and Biomedical Sciences “Mario Serio”University of FlorenceFlorenceItaly
  2. 2.Andrology, Women’s Endocrinology and Gender Inconguence UnitAzienda Ospedaliera Universitaria CareggiFlorenceItaly
  3. 3.Medicine and Surgery, Section of Endocrinology, Federico IIUniversity of NaplesNaplesItaly
  4. 4.Endocrinology Unit, Medical-Geriatric DepartmentAzienda Ospedaliera Universitaria CareggiFlorenceItaly
  5. 5.Istituto Nazionale Biostrutture e BiosistemiRomeItaly

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