Amyopathic Dermatomyositis: Definitions, Diagnosis, and Management
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Amyopathic dermatomyositis can be a challenging diagnosis because patients lack traditional muscle findings. “Clinically amyopathic” dermatomyositis (CADM) accounts for the presence of subclinical muscle disease in some of these patients. These patients represent a substantial minority of dermatomyositis cases and have similar co-morbidities to “classic” dermatomyositis patients, including interstitial lung disease and malignancy. Clinically amyopathic dermatomyositis patients should not be considered as a distinct clinical entity from “classic” dermatomyositis, as they share antibody sub-types and associated co-morbidities, likely representing clinical spectrum of a common disease. It is essential for the clinician to be familiar with the clinical presentation of clinically amyopathic dermatomyositis, in order to facilitate early, accurate diagnosis and appropriate clinical management.
KeywordsDermatomyositis Clinically amyopathic Hypomyopathic Premyopathic
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Conflict of Interest
Elizabeth E. Bailey and David F. Fiorentino declare that they have no conflicts of interest.
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This article does not contain any studies with human or animal subjects performed by any of the authors.
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