Current Rheumatology Reports

, 15:370

Outcome Assessments in Rheumatoid Arthritis

  • Katarzyna Gilek-Seibert
  • Kara Prescott
  • Salahuddin Kazi
Part of the following topical collections:
  1. Topical Collection on Rheumatoid Arthritis


Increasing evidence suggests low disease activity or remission is achievable in rheumatoid arthritis (RA). Using a treat to target strategy (T2T) has been shown to achieve these targets of remission or low disease activity in RA. In order to successfully treat to target, rheumatologists need reliable measures of disease activity to switch and/or escalate therapy to achieve or maintain therapeutic targets. Multiple disease-activity measures have been developed for both research and clinical practice. For clinical practice, the American College of Rheumatology (ACR) has recommended the PAS, PAS II, RAPID 3, CDAI, DAS 28, and SDAI for measuring disease activity in rheumatoid arthritis. Each of these measures has strengths and limitations, but they all accurately reflect disease activity, discriminate well between disease states, and are feasible to perform in the clinical setting. Implementation in the clinical setting can be optimized through leveraging technology and systems redesign. Tools such as web-based and smartphone applications have been developed to increase the ease with which these measures can be deployed. Disease-activity measurement in rheumatoid arthritis is included in the rheumatoid arthritis quality measures group in the Centers for Medicare and Medicaid Services’ incentive-based Physician Quality Reporting System.


Rheumatoid arthritis (RA) Disease activity measures Outcomes Treat to target strategy Patient-reported outcomes ACR American College of Rheumatology EULAR European league against Rheumatism Guidelines RAPID 3 PAS PAS II DAS DAS 28 SDAI CDAI Medical apps 


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Katarzyna Gilek-Seibert
    • 1
  • Kara Prescott
    • 1
  • Salahuddin Kazi
    • 1
  1. 1.Division of Rheumatic DiseasesUT Southwestern Medical CenterDallasUSA

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