Spondyloarthritis Associated with Acne Conglobata, Hidradenitis Suppurativa and Dissecting Cellulitis of the Scalp: A Review with Illustrative Cases
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To review and highlight the association of acne conglobata, hidradenitis suppurativa, and dissecting cellulitis of the scalp with inflammatory arthritic conditions, we report five illustrative patients with this association, and a review of the literature. All our patients were African-American males, and their skin disease present before the onset of arthritis. Both asymmetric peripheral arthritis and axial disease can occur. The arthritis is usually insidious and lacks association with rheumatoid factor and HLA-B27. Imaging of peripheral joints can reveal erosions, periosteal bone reaction and new bone formation. When the axial skeleton is involved, imaging can reveal sacroiliitis, syndesmophyte formation. NSAIDs, oral and intra-articular steroids, DMARDs and TNF alpha antagonists have all been used with success. Controlled trials with larger numbers of patients are needed to assess which treatment options are the most effective for this group of patients.
KeywordsAnkylosing spondylitis Sacroiliitis Spondyloarthropathy Seronegative arthritis Treatment TNF-inhibitors HLA-B27 Acne conglobata Hidradenitis suppurativa Dissecting cellulitis of the scalp Inflammatory arthritic
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Conflict of Interest
Debbie T. Lim declares that she has no conflicts of interest.
Neena M. James declares that she has no conflicts of interest.
Sobia Hassan declares that she has no conflicts of interest.
Muhammad Asim Khan declares that he has no conflicts of interest.
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This article does not contain any studies with human or animal subjects performed by any of the authors.
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