Current Rheumatology Reports

, Volume 11, Issue 3, pp 205–211 | Cite as

The use of doppler ultrasound to evaluate lesions of localized scleroderma

  • Suzanne C. Li
  • Melissa S. Liebling


Doppler ultrasound shows great promise for the evaluation of localized scleroderma (LS). Disease-related structural changes, such as tissue thickening, atrophy, and architectural alterations, can be readily detected using ultrasound. High spatial resolution enables monitoring of changes in tissue thickness over the course of disease and treatment. Doppler ultrasound may also aid assessment of disease activity. Both abnormal tissue echogenicity and vascularity levels can represent disease activity in some patients. Because tissue thickness, echogenicity, and vascularity vary with body site and age, accurate ultrasound evaluation of the LS lesion requires comparison to a control site, ideally the contralateral side. Evaluation of deeper tissues is important, as disease involvement may reside primarily below the dermis. Further study is needed to determine the validity, sensitivity, and reliability of ultrasound for LS.


Scleroderma Cartilage Oligomeric Matrix Protein Tissue Thickness Calcipotriol Lichen Sclerosus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Current Medicine Group, LLC 2009

Authors and Affiliations

  1. 1.Department of Pediatrics, Joseph M. Sanzari Children’s HospitalHackensack University Medical CenterHackensackUSA

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