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Current Rheumatology Reports

, Volume 2, Issue 4, pp 324–329 | Cite as

Long-term cardiac sequelae of Kawasaki disease

  • David R. Fulton
  • Jane W. Newburger
Article

Abstract

Kawasaki disease is the leading cause of acquired heart disease in childhood. Despite treatment with intravenous gamma globulin, 2% to 4% of patients have coronary abnormalities. Those with giant aneurysms are at risk for stenosis and myocardial ischemia/infarction, and require aggressive anticoagulation with frequent follow-up, including stress testing and coronary angiography. In rare cases, patients will have coronary artery bypass grafting. Those with less severe coronary involvement need antiplatelet therapy and infrequent noninvasive testing. Patients with normal echos after the acute phase are not treated, but the future impact of the disease is not certain particularly in the setting of adult onset coronary artery disease.

Keywords

Kawasaki Disease Coronary Flow Reserve Coronary Artery Aneurysm Coronary Artery Lesion Giant Aneurysm 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Current Science Inc 2000

Authors and Affiliations

  • David R. Fulton
    • 1
  • Jane W. Newburger
    • 1
  1. 1.Department of CardiologyChildren’s Hospital of BostonBostonUSA

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