Current Psychiatry Reports

, Volume 12, Issue 2, pp 111–115 | Cite as

Peripheral Vasculopathy Associated with Psychostimulant Treatment in Children with Attention-Deficit/Hyperactivity Disorder

  • Zheya Jenny Yu
  • Caroline Parker-Kotler
  • Kathleen Tran
  • Ronald A. Weller
  • Elizabeth B. Weller


Psychostimulants (methylphenidate and amphetamine salt) are the pharmacologic treatment of choice for children with attention-deficit/hyperactivity disorder. However, psychostimulants have been linked to a variety of vascular problems, including peripheral vasculopathy. This article describes four boys with attention-deficit/hyperactivity disorder who developed vasculopathy during treatment with psychostimulants.


Psychostimulants Vasculopathy 



Drs. Ronald and Elizabeth Weller are co-owners of the Children’s Interview for Psychiatric Syndromes (and the parent’s version) and have received annual royalties from copyright ownership of this diagnostic interview. Dr. Elizabeth Weller was the principal investigator for a grant from GlaxoSmithKline to investigate the tolerability and efficacy of lamotrigine in children and adolescents diagnosed with bipolar disorder. No other potential conflicts of interest relevant to this article were reported.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Zheya Jenny Yu
    • 1
  • Caroline Parker-Kotler
    • 2
  • Kathleen Tran
    • 3
  • Ronald A. Weller
    • 4
  • Elizabeth B. Weller
    • 5
  1. 1.Hall-Mercer MH/MR Center, Pennsylvania HospitalUniversity of Pennsylvania Health SystemPhiladelphiaUSA
  2. 2.Greentree PediatricsMarltonUSA
  3. 3.Department of MedicineMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  4. 4.Department of PsychiatryUniversity of PennsylvaniaPhiladelphiaUSA
  5. 5.The Children’s Hospital of PhiladelphiaUniversity of PennsylvaniaPhiladelphiaUSA

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