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Peripheral Vasculopathy Associated with Psychostimulant Treatment in Children with Attention-Deficit/Hyperactivity Disorder

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Abstract

Psychostimulants (methylphenidate and amphetamine salt) are the pharmacologic treatment of choice for children with attention-deficit/hyperactivity disorder. However, psychostimulants have been linked to a variety of vascular problems, including peripheral vasculopathy. This article describes four boys with attention-deficit/hyperactivity disorder who developed vasculopathy during treatment with psychostimulants.

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Disclosure

Drs. Ronald and Elizabeth Weller are co-owners of the Children’s Interview for Psychiatric Syndromes (and the parent’s version) and have received annual royalties from copyright ownership of this diagnostic interview. Dr. Elizabeth Weller was the principal investigator for a grant from GlaxoSmithKline to investigate the tolerability and efficacy of lamotrigine in children and adolescents diagnosed with bipolar disorder. No other potential conflicts of interest relevant to this article were reported.

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Authors and Affiliations

  1. Hall-Mercer MH/MR Center, Pennsylvania Hospital, University of Pennsylvania Health System, 245 South 8th Street, Philadelphia, PA, 19107, USA

    Zheya Jenny Yu

  2. Greentree Pediatrics, 127 Church Road, Marlton, NJ, 08053, USA

    Caroline Parker-Kotler

  3. Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    Kathleen Tran

  4. Department of Psychiatry, University of Pennsylvania, 3600 Market Street, 7th Floor, Philadelphia, PA, 19104, USA

    Ronald A. Weller

  5. The Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, USA

    Elizabeth B. Weller

Authors
  1. Zheya Jenny Yu
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  2. Caroline Parker-Kotler
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  3. Kathleen Tran
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  4. Ronald A. Weller
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  5. Elizabeth B. Weller
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Correspondence to Zheya Jenny Yu.

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Yu, Z.J., Parker-Kotler, C., Tran, K. et al. Peripheral Vasculopathy Associated with Psychostimulant Treatment in Children with Attention-Deficit/Hyperactivity Disorder. Curr Psychiatry Rep 12, 111–115 (2010). https://doi.org/10.1007/s11920-010-0093-y

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  • DOI: https://doi.org/10.1007/s11920-010-0093-y

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