Current Prostate Reports

, Volume 5, Issue 1, pp 13–17 | Cite as

Prostate cancer detection strategies

  • Timothy C. Brand
  • Javier Hernandez
  • Edith D. Canby-Hagino
  • Joseph W. Basler
  • Ian M. Thompson
Article
  • 8 Downloads

Abstract

Prostate cancer is the most common malignancy in men and, as a result, there has been a nationwide emphasis on screening and detection. With the widespread use of the prostate-specific antigen (PSA), prostate cancer screening effectively detects localized prostate cancer. However, recent reports have identified a significant proportion of prostate cancer in men with low PSA levels. Many of these cancers are higher-grade malignancies. Consequently, PSA may function more effectively as a screening tool when applied over a continuum that is associated with degree of risk, rather than a binary measure. Other markers are currently being investigated. Ideally, a marker will identify the malignancy that is a clinical threat, thereby avoiding intervention for indolent disease. Prevention strategies may be employed for higher-risk patients, and these strategies eventually may be tailored to genetic or other risks.

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Copyright information

© Current Medicine Group LLC 2007

Authors and Affiliations

  • Timothy C. Brand
    • 1
  • Javier Hernandez
  • Edith D. Canby-Hagino
  • Joseph W. Basler
  • Ian M. Thompson
  1. 1.Department of UrologyUniversity of Texas Health Science CenterSan AntonioUSA

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