It IS a Tumor- Current Review of Headache and Brain Tumor
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“Do I have a tumor?” This is a question in every person’s mind when first confronted with a new-onset headache, a question that causes considerable anxiety among patients, leading them to seek medical evaluation. This publication reviews the current literature with respect to the epidemiology, pathophysiology presentation, and treatment of headaches in association with intracranial neoplasm.
KeywordsTumor Headache Epidemiology Pathophysiology Intracranial neoplasm
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
- 3.•Forsyth PA, Posner JB. Headaches in patients with brain tumors: a study of 111 patients. Neurology. 1993;43(9):1678–83. This reference is important since it is the first prospective study to formally test whether the features of headaches among brain tumor patients is consistent with the “classic” presentation.PubMedCrossRefGoogle Scholar
- 4.•Headache Classification Subcommittee of the International Headache Society. The international classification of headache disorders: 2nd edition. Cephalalgia. 2004;24 Suppl 1:9–160. This reference is important because it contains the criteria for tumor associated headache as well as the other headache disorders. The criteria are necessary to be able to standardize research methods and subject populations between studies regarding patients presenting with headache.Google Scholar
- 6.••American Academy of Neurology: Practice Guidelines. Evidence-Based Guidelines in the Primary Care Setting:Neuroimaging in Patients with Nonacute Headache. http://tools.aan.com/professionals/practice/pdfs/gl0088.pdf. This is a very important reference since it defines the “red flags” that clinicians should be aware of when assessing patients with headache and could serve as a useful guide for when to do additional diagnostics other than the history and physical examination.
- 16.•Valentinis L, Tuniz F, Valent F, Mucchiut M, Little D, Skrap M, et al. Headache attributed to intracranial tumours: a prospective cohort study. Cephalalgia. 2010;30(4):389–98. This reference is important since it is the most recent prospective study to examine patients with brain tumor and headache using the most recent iteration of the International Headache Society Classification criteria.PubMedGoogle Scholar
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